Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2368248..2368393 Replicon chromosome
Accession NZ_CP110661
Organism Klebsiella pneumoniae strain B431

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2368255..2368357 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2368248..2368393 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OOS97_RS11585 2363779..2365212 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
OOS97_RS11590 2365328..2365567 + 240 WP_002911393.1 YebV family protein -
OOS97_RS11595 2365665..2365856 + 192 WP_002911395.1 YebW family protein -
OOS97_RS11600 2365853..2366506 - 654 WP_009307541.1 protein-serine/threonine phosphatase -
OOS97_RS11605 2366663..2367631 + 969 WP_004151446.1 VirK/YbjX family protein -
OOS97_RS11610 2367736..2367879 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 2368248..2368393 + 146 - - Antitoxin
- 2368255..2368357 - 103 - - Toxin
OOS97_RS11615 2368516..2368854 - 339 WP_009307539.1 YebY family protein -
OOS97_RS11620 2368871..2369740 - 870 WP_009307538.1 copper homeostasis membrane protein CopD -
OOS97_RS11625 2369744..2370118 - 375 WP_004151448.1 CopC domain-containing protein YobA -
OOS97_RS11630 2370231..2370461 + 231 WP_002911406.1 DNA polymerase III subunit theta -
OOS97_RS11635 2370540..2371199 + 660 WP_002911407.1 exodeoxyribonuclease X -
OOS97_RS11640 2371203..2373263 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T264103 NZ_CP110661:c2368357-2368255 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT264103 NZ_CP110661:2368248-2368393 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References