26410

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 390450..390813 Replicon chromosome
Accession NC_017271
Organism Xanthomonas campestris pv. raphani 756C

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag XCR_RS01585 Protein ID WP_011270059.1
Coordinates 390679..390813 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag XCR_RS01580 Protein ID WP_011038999.1
Coordinates 390450..390602 (+) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XCR_RS01545 385622..386305 - 684 WP_011039005.1 dTMP kinase -
XCR_RS01550 386640..386975 - 336 WP_014506229.1 hypothetical protein -
XCR_RS01555 386979..387182 - 204 WP_014506230.1 hypothetical protein -
XCR_RS01560 387179..388096 - 918 WP_014506231.1 hypothetical protein -
XCR_RS01565 388199..388558 - 360 WP_011039002.1 hypothetical protein -
XCR_RS01570 388641..389102 - 462 WP_012439505.1 roadblock/LC7 domain-containing protein -
XCR_RS01575 389416..390339 + 924 WP_011039000.1 arginase -
XCR_RS01580 390450..390602 + 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
XCR_RS01585 390679..390813 + 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
XCR_RS01590 391044..391253 + 210 WP_011038998.1 CsbD family protein -
XCR_RS01595 391414..392703 + 1290 WP_043922084.1 tryptophan--tRNA ligase -
XCR_RS01600 392787..393731 + 945 WP_043921547.1 MBL fold metallo-hydrolase -
XCR_RS01605 393896..395548 + 1653 WP_043921548.1 M28 family peptidase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T26410 WP_011270059.1 NC_017271:390679-390813 [Xanthomonas campestris pv. raphani 756C]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T26410 NC_017271:390679-390813 [Xanthomonas campestris pv. raphani 756C]
ATGAAGCGTGCAATTGCATTGTTGGTGCTGTCGATGTTGTCGGTTGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCCGCGCGCAAGTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT26410 WP_011038999.1 NC_017271:390450-390602 [Xanthomonas campestris pv. raphani 756C]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT26410 NC_017271:390450-390602 [Xanthomonas campestris pv. raphani 756C]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTCTCGGCCGGCATGATGACTGGCTGTAACACCATGGCTGGTGC
CGGAAAGGACATGCAGGGTGCGGGTGACAAGGTCGAGAAGACCGCCGACAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0


Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References