Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/RelE-RHH
Location 41654..42210 Replicon plasmid unnamed1
Accession NZ_CP110655
Organism Aeromonas salmonicida strain AS1

Toxin (Protein)


Gene name relE Uniprot ID A0A2H9U809
Locus tag ONZ57_RS22680 Protein ID WP_042468953.1
Coordinates 41654..41929 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ONZ57_RS22685 Protein ID WP_174416604.1
Coordinates 41929..42210 (-) Length 94 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ONZ57_RS22655 (ONZ57_22660) 36712..37382 + 671 Protein_48 IS5 family transposase -
ONZ57_RS22660 (ONZ57_22665) 37574..38605 - 1032 WP_088814095.1 IS630 family transposase -
ONZ57_RS22665 (ONZ57_22670) 38800..39717 - 918 WP_076611341.1 IS5-like element ISAs4 family transposase -
ONZ57_RS22670 (ONZ57_22675) 39766..39951 - 186 WP_088814096.1 hypothetical protein -
ONZ57_RS22675 (ONZ57_22680) 39953..40867 - 915 WP_042468951.1 TOMM precursor leader peptide-binding protein -
ONZ57_RS22680 (ONZ57_22685) 41654..41929 - 276 WP_042468953.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ONZ57_RS22685 (ONZ57_22690) 41929..42210 - 282 WP_174416604.1 ribbon-helix-helix domain-containing protein Antitoxin
ONZ57_RS22690 (ONZ57_22695) 42422..42982 + 561 WP_042468955.1 recombinase family protein -
ONZ57_RS22695 (ONZ57_22700) 42986..46014 + 3029 Protein_56 Tn3 family transposase -
ONZ57_RS22700 (ONZ57_22705) 46049..46723 + 675 Protein_57 IS21 family transposase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - aopN / acr1 / acr2 / ascX / ascY / ascV / acrR / acrG / acrV / acrH / aopB / aopD / exsC / exsE / exsB / exsA / exsD / ascB / ascC / ascD / ascE / ascF / ascG / ascH / ascI / ascJ / ascK / ascL / ati1 / ati2 / aopO / aopO / aopO / sycO / ascU / ascT / ascS / ascR / ascQ / ascP / ascO / ascN 1..62719 62719
- inside IScluster/Tn - aopO / aopO / aopO / sycO 30830..55181 24351


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 92 a.a.        Molecular weight: 10685.43 Da        Isoelectric Point: 9.5291

>T264078 WP_042468953.1 NZ_CP110655:c41929-41654 [Aeromonas salmonicida]
MELKWTSKALSDLARLYEFLALANKPAAARAVQALTQAPTILLTNPRIGEQLFQFEPREVRRILVGEYEVRYEILDSIIY
VLRLWHTRENR

Download         Length: 276 bp


Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10351.80 Da        Isoelectric Point: 5.6624

>AT264078 WP_174416604.1 NZ_CP110655:c42210-41929 [Aeromonas salmonicida]
MKGNMTQATTKVLTAHVPLPMADKVDQMAARLERSRGWIMKQALSAWLAQEEDRDRLTQEALADVDAGRVIDHLAVQAWA
DSLNTDQPLSVPR

Download         Length: 282 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A2H9U809


Antitoxin

Source ID Structure

References