Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 1504435..1505054 Replicon chromosome
Accession NZ_CP110650
Organism Aeromonas salmonicida strain BG

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag ONZ60_RS07230 Protein ID WP_085044624.1
Coordinates 1504758..1505054 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ONZ60_RS07225 Protein ID WP_085044625.1
Coordinates 1504435..1504755 (-) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ONZ60_RS07205 (ONZ60_07205) 1499504..1500631 - 1128 WP_005312969.1 succinyl-diaminopimelate desuccinylase -
ONZ60_RS07210 (ONZ60_07210) 1500651..1501001 - 351 WP_005312972.1 ArsC family reductase -
ONZ60_RS07215 (ONZ60_07215) 1501218..1502129 - 912 WP_011898932.1 LysR family transcriptional regulator -
ONZ60_RS07220 (ONZ60_07220) 1502849..1504216 - 1368 WP_085044626.1 hypothetical protein -
ONZ60_RS07225 (ONZ60_07225) 1504435..1504755 - 321 WP_085044625.1 putative addiction module antidote protein Antitoxin
ONZ60_RS07230 (ONZ60_07230) 1504758..1505054 - 297 WP_085044624.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ONZ60_RS07235 (ONZ60_07235) 1505775..1506473 - 699 WP_085044623.1 phage virion morphogenesis protein -
ONZ60_RS07240 (ONZ60_07240) 1506485..1508098 - 1614 WP_085044622.1 hypothetical protein -
ONZ60_RS07245 (ONZ60_07245) 1508095..1508643 - 549 WP_085044621.1 hypothetical protein -
ONZ60_RS07250 (ONZ60_07250) 1508640..1509521 - 882 WP_085044620.1 hypothetical protein -
ONZ60_RS07255 (ONZ60_07255) 1509518..1509754 - 237 WP_139804925.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1502849..1535265 32416


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Cro/C1-type helix-turn-helix domain

(50-94)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11025.77 Da        Isoelectric Point: 10.1760

>T264074 WP_085044624.1 NZ_CP110650:c1505054-1504758 [Aeromonas salmonicida]
MREIIKTNVFDRWFDSLRDARAQAKVTARIRRLGLGNPGDVKPIGEGLSEMRIDYGPGYRVYFMTKGPIIIVLLCGGDKG
TQARDIEQAKTIAAQWKD

Download         Length: 297 bp

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 11417.87 Da        Isoelectric Point: 5.0944

>AT264074 WP_085044625.1 NZ_CP110650:c1504755-1504435 [Aeromonas salmonicida]
MKDHEQTVTFSRYDAADYLKTDEDMLHYLEAVMEEGDPALIAAALGDIARARNLSQLARDVGMSREGLYKALSGEGNPTF
ATITKVAGALGLRFGVHLANPPATHA

Download         Length: 321 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References