Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 1497891..1498510 Replicon chromosome
Accession NZ_CP110648
Organism Aeromonas salmonicida strain YK

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag ONZ67_RS07165 Protein ID WP_085044624.1
Coordinates 1498214..1498510 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ONZ67_RS07160 Protein ID WP_085044625.1
Coordinates 1497891..1498211 (-) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ONZ67_RS07140 (ONZ67_07140) 1492960..1494087 - 1128 WP_005312969.1 succinyl-diaminopimelate desuccinylase -
ONZ67_RS07145 (ONZ67_07145) 1494107..1494457 - 351 WP_005312972.1 ArsC family reductase -
ONZ67_RS07150 (ONZ67_07150) 1494674..1495585 - 912 WP_011898932.1 LysR family transcriptional regulator -
ONZ67_RS07155 (ONZ67_07155) 1496305..1497672 - 1368 WP_085044626.1 hypothetical protein -
ONZ67_RS07160 (ONZ67_07160) 1497891..1498211 - 321 WP_085044625.1 putative addiction module antidote protein Antitoxin
ONZ67_RS07165 (ONZ67_07165) 1498214..1498510 - 297 WP_085044624.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ONZ67_RS07170 (ONZ67_07170) 1499231..1499929 - 699 WP_085044623.1 phage virion morphogenesis protein -
ONZ67_RS07175 (ONZ67_07175) 1499941..1501554 - 1614 WP_085044622.1 hypothetical protein -
ONZ67_RS07180 (ONZ67_07180) 1501551..1502099 - 549 WP_085044621.1 hypothetical protein -
ONZ67_RS07185 (ONZ67_07185) 1502096..1502977 - 882 WP_085044620.1 hypothetical protein -
ONZ67_RS07190 (ONZ67_07190) 1502974..1503210 - 237 WP_139804925.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1496305..1528721 32416


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Cro/C1-type helix-turn-helix domain

(50-94)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11025.77 Da        Isoelectric Point: 10.1760

>T264073 WP_085044624.1 NZ_CP110648:c1498510-1498214 [Aeromonas salmonicida]
MREIIKTNVFDRWFDSLRDARAQAKVTARIRRLGLGNPGDVKPIGEGLSEMRIDYGPGYRVYFMTKGPIIIVLLCGGDKG
TQARDIEQAKTIAAQWKD

Download         Length: 297 bp

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 11417.87 Da        Isoelectric Point: 5.0944

>AT264073 WP_085044625.1 NZ_CP110648:c1498211-1497891 [Aeromonas salmonicida]
MKDHEQTVTFSRYDAADYLKTDEDMLHYLEAVMEEGDPALIAAALGDIARARNLSQLARDVGMSREGLYKALSGEGNPTF
ATITKVAGALGLRFGVHLANPPATHA

Download         Length: 321 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References