Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1994313..1994458 Replicon chromosome
Accession NZ_CP110638
Organism Klebsiella pneumoniae strain K201054

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1994349..1994451 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1994313..1994458 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OO068_RS10775 1989443..1991503 + 2061 WP_004151449.1 oligopeptidase B -
OO068_RS10780 1991507..1992166 - 660 WP_002911407.1 exodeoxyribonuclease X -
OO068_RS10785 1992245..1992475 - 231 WP_002911406.1 DNA polymerase III subunit theta -
OO068_RS10790 1992588..1992962 + 375 WP_004151448.1 CopC domain-containing protein YobA -
OO068_RS10795 1992966..1993835 + 870 WP_048331959.1 copper homeostasis membrane protein CopD -
OO068_RS10800 1993852..1994190 + 339 WP_016529031.1 YebY family protein -
- 1994313..1994458 - 146 - - Antitoxin
- 1994349..1994451 + 103 - - Toxin
OO068_RS10805 1994827..1994970 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
OO068_RS10810 1995075..1996043 - 969 WP_074185275.1 VirK/YbjX family protein -
OO068_RS10815 1996200..1996853 + 654 WP_032447686.1 protein-serine/threonine phosphatase -
OO068_RS10820 1996850..1997041 - 192 WP_002911395.1 YebW family protein -
OO068_RS10825 1997139..1997378 - 240 WP_002911393.1 YebV family protein -
OO068_RS10830 1997494..1998927 - 1434 WP_258785491.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T264058 NZ_CP110638:1994349-1994451 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT264058 NZ_CP110638:c1994458-1994313 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References