264038

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 1400558..1401474 Replicon chromosome
Accession NZ_CP110634
Organism Bacillus subtilis strain MG-1

Toxin (Protein)


Gene name spoIISA Uniprot ID -
Locus tag OOZ27_RS07605 Protein ID WP_015715744.1
Coordinates 1400728..1401474 (-) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID -
Locus tag OOZ27_RS07600 Protein ID WP_015715743.1
Coordinates 1400558..1400728 (-) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OOZ27_RS07565 (1397417) 1397417..1397746 + 330 WP_003232660.1 XkdW family protein -
OOZ27_RS07570 (1397743) 1397743..1397907 + 165 WP_015715740.1 XkdX family protein -
OOZ27_RS07575 (1397951) 1397951..1398790 + 840 WP_015715741.1 phage-like element PBSX protein XepA -
OOZ27_RS07580 (1398843) 1398843..1399112 + 270 WP_003232655.1 hemolysin XhlA family protein -
OOZ27_RS07585 (1399125) 1399125..1399388 + 264 WP_014479566.1 phage holin -
OOZ27_RS07590 (1399401) 1399401..1400294 + 894 WP_015715742.1 N-acetylmuramoyl-L-alanine amidase -
OOZ27_RS07595 (1400332) 1400332..1400472 - 141 WP_144460135.1 three component toxin-antitoxin-antitoxin system antitoxin SpoIISC -
OOZ27_RS07600 (1400558) 1400558..1400728 - 171 WP_015715743.1 three component toxin-antitoxin-antitoxin system antitoxin SpoIISB Antitoxin
OOZ27_RS07605 (1400728) 1400728..1401474 - 747 WP_015715744.1 toxin-antitoxin-antitoxin system toxin SpoIISA Toxin
OOZ27_RS07610 (1401584) 1401584..1402585 - 1002 WP_014479569.1 inorganic phosphate transporter -
OOZ27_RS07615 (1402598) 1402598..1403215 - 618 WP_003218470.1 DUF47 domain-containing protein -
OOZ27_RS07620 (1403491) 1403491..1404807 - 1317 WP_015252262.1 serine/threonine exchanger -
OOZ27_RS07625 (1405196) 1405196..1406146 + 951 WP_015715745.1 ring-cleaving dioxygenase -
OOZ27_RS07630 (1406255) 1406255..1406350 + 96 Protein_1441 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-238)

Antitoxin

Antitoxin SpoIISB

(1-56)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29043.47 Da        Isoelectric Point: 4.6191

>T264038 WP_015715744.1 NZ_CP110634:c1401474-1400728 [Bacillus subtilis]
MVLFFQIMVWCIVAGLGLYVYATWRFEAKVKEKMSAIRKTWYLLFVLGAMVYWTYEPTSLFTHWERYLIVAVSFALIDAF
IFLSAYVKKLAGSELETDTREILEENNEMLHIYLNRLKTYQYLLKNEPIHVYYGSIDAYAEGIDKLLKTYADKMNLTASL
CHYSTQADKDRLTEHMDDPADVQTRLDRKDVYYDQYGKVVLIPFTIETQNYVIKLTSDSIVTEFDYLLFTSLTSIYDLVL
PIEEEGEG

Download         Length: 747 bp

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6682.74 Da        Isoelectric Point: 11.1467

>AT264038 WP_015715743.1 NZ_CP110634:c1400728-1400558 [Bacillus subtilis]
MERAFQNRCEPRAAKPFKILKKRSTTSVASYQVSPHTARIFKENERLIDEYKRKRA

Download         Length: 171 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References