Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 2175187..2175797 Replicon chromosome
Accession NZ_CP110622
Organism Prosthecochloris sp. SCSIO W1103

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag OO005_RS09985 Protein ID WP_110023745.1
Coordinates 2175187..2175492 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OO005_RS09990 Protein ID WP_110023746.1
Coordinates 2175489..2175797 (+) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OO005_RS09975 (OO005_09975) 2170437..2173205 + 2769 WP_265354097.1 phosphoenolpyruvate carboxylase -
OO005_RS09980 (OO005_09980) 2173286..2174842 + 1557 WP_265354098.1 YifB family Mg chelatase-like AAA ATPase -
OO005_RS09985 (OO005_09985) 2175187..2175492 + 306 WP_110023745.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OO005_RS09990 (OO005_09990) 2175489..2175797 + 309 WP_110023746.1 putative addiction module antidote protein Antitoxin
OO005_RS09995 (OO005_09995) 2175963..2176382 + 420 WP_110023747.1 nuclear transport factor 2 family protein -
OO005_RS10000 (OO005_10000) 2176470..2176991 + 522 WP_110023748.1 class IV adenylate cyclase -
OO005_RS10005 (OO005_10005) 2177051..2177464 + 414 WP_265354099.1 GNAT family N-acetyltransferase -
OO005_RS10010 (OO005_10010) 2177803..2178648 + 846 WP_265354100.1 hypothetical protein -
OO005_RS10015 (OO005_10015) 2179080..2179631 + 552 WP_265354101.1 DUF2059 domain-containing protein -
OO005_RS10020 (OO005_10020) 2179712..2180176 + 465 WP_265354102.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-91)

Antitoxin

Uncharacterized protein HI1420

(5-91)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11500.16 Da        Isoelectric Point: 10.6525

>T264033 WP_110023745.1 NZ_CP110622:2175187-2175492 [Prosthecochloris sp. SCSIO W1103]
MNTFIRSNEFDRWLSNLSDQKAKARILARLRSAMHGNFGDCEPVGEGVSEMRIHVGAGYRVYYTRTGTTVYFLLGGGSKS
TQRKDIKNLKKLARKIKETEQ

Download         Length: 306 bp

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11007.38 Da        Isoelectric Point: 4.8182

>AT264033 WP_110023746.1 NZ_CP110622:2175489-2175797 [Prosthecochloris sp. SCSIO W1103]
VNSEFATFDIADYLDNEEVITEYLSAATEDPNPDVFIAALGDVAKARGMTQIAKDSGLGRESLYKALSAGSHPRFETINA
VLHALGVKIAIIPADRRQKKTS

Download         Length: 309 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References