Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2404197..2404291 Replicon chromosome
Accession NC_017265
Organism Yersinia pestis biovar Medievalis str. Harbin 35

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2404198..2404291 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2404197..2404291 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
YPC_RS11240 2399390..2401469 - 2080 Protein_2112 flagellar biosynthesis protein FlhA -
YPC_RS11245 2401469..2402628 - 1160 Protein_2113 flagellar type III secretion system protein FlhB -
YPC_RS11250 2403160..2403618 + 459 WP_002211098.1 hypothetical protein -
YPC_RS11255 2403612..2403938 + 327 WP_002211097.1 DUF1493 family protein -
- 2404197..2404291 + 95 - - Antitoxin
- 2404198..2404291 - 94 - - Toxin
YPC_RS11265 2404461..2404802 - 342 WP_002211095.1 YebY family protein -
YPC_RS11270 2404899..2405783 - 885 WP_002211094.1 copper homeostasis membrane protein CopD -
YPC_RS11275 2405786..2406172 - 387 WP_002211093.1 CopC domain-containing protein YobA -
YPC_RS11280 2406569..2407078 - 510 WP_002211092.1 non-heme ferritin -
YPC_RS11285 2407479..2407709 + 231 WP_002211091.1 DNA polymerase III subunit theta -
YPC_RS11290 2407769..2408720 - 952 Protein_2121 prolyl aminopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences

Toxin        


Download         Length: 94 bp

>T26397 NC_017265:c2404291-2404198 [Yersinia pestis biovar Medievalis str. Harbin 35]
TAAGCCTACATTAATACCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATCAGGAATCGTA
TTCGGTCTTTTTTT

Antitoxin


Download         Length: 95 bp

>AT26397 NC_017265:2404197-2404291 [Yersinia pestis biovar Medievalis str. Harbin 35]
TAAAAAAAGACCGAATACGATTCCTGATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGT
ATTAATGTAGGCTTA

Structures

Antitoxin

Download structure file

Antitoxin

Download structure file

References