Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 3594068..3594627 Replicon chromosome
Accession NZ_CP110615
Organism Rhodococcus sp. 75

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag RHODO2019_RS17525 Protein ID WP_265382980.1
Coordinates 3594068..3594436 (-) Length 123 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag RHODO2019_RS17530 Protein ID WP_265382981.1
Coordinates 3594433..3594627 (-) Length 65 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RHODO2019_RS17505 (RHODO2019_17505) 3590225..3591232 - 1008 WP_265382976.1 DUF2791 family P-loop domain-containing protein -
RHODO2019_RS17510 (RHODO2019_17510) 3591229..3592026 - 798 WP_265382977.1 hypothetical protein -
RHODO2019_RS17515 (RHODO2019_17515) 3592130..3593092 - 963 WP_265382978.1 ROK family protein -
RHODO2019_RS17520 (RHODO2019_17520) 3593537..3593806 - 270 WP_265382979.1 helix-turn-helix domain-containing protein -
RHODO2019_RS17525 (RHODO2019_17525) 3594068..3594436 - 369 WP_265382980.1 VapC toxin family PIN domain ribonuclease Toxin
RHODO2019_RS17530 (RHODO2019_17530) 3594433..3594627 - 195 WP_265382981.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
RHODO2019_RS17535 (RHODO2019_17535) 3594711..3597869 - 3159 WP_265382982.1 DEAD/DEAH box helicase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-44)


Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 12763.63 Da        Isoelectric Point: 4.9949

>T263965 WP_265382980.1 NZ_CP110615:c3594436-3594068 [Rhodococcus sp. 75]
VSVLVDTSVWVDHLRTGNPRLAALLEQSRVLIHPWVLGELALGGVIRNAEVSTLLGALPRAPLVSDSELVGFIQTQALHG
RGVGYVDAQLLASTVLDPDAVLWSADKGLSAAAAELGVAHQT

Download         Length: 369 bp

Antitoxin


Download         Length: 65 a.a.        Molecular weight: 7024.09 Da        Isoelectric Point: 9.1348

>AT263965 WP_265382981.1 NZ_CP110615:c3594627-3594433 [Rhodococcus sp. 75]
MRTTIALDDDLVAEAQRLTGTTEKAALVREALTALIERESAHRLARLGGTMPELQIAPRRRTAP

Download         Length: 195 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References