Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 3588390..3588928 Replicon chromosome
Accession NZ_CP110615
Organism Rhodococcus sp. 75

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag RHODO2019_RS17495 Protein ID WP_265382974.1
Coordinates 3588650..3588928 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag RHODO2019_RS17490 Protein ID WP_265382973.1
Coordinates 3588390..3588653 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RHODO2019_RS17470 (RHODO2019_17470) 3584464..3586110 + 1647 WP_265382969.1 ATP-binding domain-containing protein -
RHODO2019_RS17475 (RHODO2019_17475) 3586185..3586448 + 264 WP_265382970.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
RHODO2019_RS17480 (RHODO2019_17480) 3586445..3586837 + 393 WP_265382971.1 type II toxin-antitoxin system VapC family toxin -
RHODO2019_RS17485 (RHODO2019_17485) 3586857..3588335 - 1479 WP_265382972.1 serine/threonine-protein kinase -
RHODO2019_RS17490 (RHODO2019_17490) 3588390..3588653 + 264 WP_265382973.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
RHODO2019_RS17495 (RHODO2019_17495) 3588650..3588928 + 279 WP_265382974.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
RHODO2019_RS17500 (RHODO2019_17500) 3588972..3590228 - 1257 WP_265382975.1 DUF2791 family P-loop domain-containing protein -
RHODO2019_RS17505 (RHODO2019_17505) 3590225..3591232 - 1008 WP_265382976.1 DUF2791 family P-loop domain-containing protein -
RHODO2019_RS17510 (RHODO2019_17510) 3591229..3592026 - 798 WP_265382977.1 hypothetical protein -
RHODO2019_RS17515 (RHODO2019_17515) 3592130..3593092 - 963 WP_265382978.1 ROK family protein -
RHODO2019_RS17520 (RHODO2019_17520) 3593537..3593806 - 270 WP_265382979.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-67)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10313.09 Da        Isoelectric Point: 11.1310

>T263964 WP_265382974.1 NZ_CP110615:3588650-3588928 [Rhodococcus sp. 75]
VTTPLELRVGPGARRQLYRLPPRVVVAVVEFVTVTLVENPLRLTKPLVGELDGLRSARRGDYRILVRVDEDAHVVLVVRV
AHRSEAYRPPAP

Download         Length: 279 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9195.16 Da        Isoelectric Point: 4.4055

>AT263964 WP_265382973.1 NZ_CP110615:3588390-3588653 [Rhodococcus sp. 75]
VDRQRRAHTLSALVEAAQSTHDIVTITRHGRPAAVLMSADDLESLQETVFWLSQPGVREDVASADAALADGSAISGAELR
AELGLDS

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References