Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 4571882..4572792 Replicon chromosome
Accession NZ_CP110535
Organism Halomonas sp. BDJS001

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag OM794_RS21215 Protein ID WP_226246486.1
Coordinates 4572328..4572792 (+) Length 155 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag OM794_RS21210 Protein ID WP_226246487.1
Coordinates 4571882..4572331 (+) Length 150 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OM794_RS21190 (OM794_21190) 4568404..4568772 - 369 WP_226246490.1 urease subunit beta -
OM794_RS21195 (OM794_21195) 4568875..4569177 - 303 WP_022521353.1 urease subunit gamma -
OM794_RS21200 (OM794_21200) 4569215..4570099 - 885 WP_226246489.1 urease accessory protein UreD -
OM794_RS21205 (OM794_21205) 4570330..4571691 - 1362 WP_226246488.1 diguanylate cyclase -
OM794_RS21210 (OM794_21210) 4571882..4572331 + 450 WP_226246487.1 DUF2384 domain-containing protein Antitoxin
OM794_RS21215 (OM794_21215) 4572328..4572792 + 465 WP_226246486.1 RES family NAD+ phosphorylase Toxin
OM794_RS21220 (OM794_21220) 4572809..4573516 - 708 WP_226246485.1 urea ABC transporter ATP-binding subunit UrtE -
OM794_RS21225 (OM794_21225) 4573516..4574352 - 837 WP_226246484.1 urea ABC transporter ATP-binding protein UrtD -
OM794_RS21230 (OM794_21230) 4574349..4575512 - 1164 WP_226246483.1 urea ABC transporter permease subunit UrtC -
OM794_RS21235 (OM794_21235) 4575516..4577135 - 1620 WP_226246482.1 urea ABC transporter permease subunit UrtB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(6-149)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(31-90)


Sequences

Toxin        


Download         Length: 155 a.a.        Molecular weight: 16810.24 Da        Isoelectric Point: 4.3640

>T263958 WP_226246486.1 NZ_CP110535:4572328-4572792 [Halomonas sp. BDJS001]
MSEVTAYRLVKRKFQETAFDGEGARLYGGRWNSPGNACVYVASTESLALLEIMVPLESYRLLNAYALLRLTLPAESILSV
GAEDLPANWREAPVPAETAELGDGWLASNQSLALAVPSVVVPRELNYMLNPAHPLFDQIIAAAEALPFQPDPRL

Download         Length: 465 bp

Antitoxin


Download         Length: 150 a.a.        Molecular weight: 16629.10 Da        Isoelectric Point: 9.8525

>AT263958 WP_226246487.1 NZ_CP110535:4571882-4572331 [Halomonas sp. BDJS001]
MDVHFTQYQPPKALAFGFWQQIGLPARGRKLHELLHEGVEYRVYPQLAKVSGIEQKALASYVDIPPATLSRRAKSGRFKM
AESDRLYRFAELFKAALDLFEGDADGARAWLLKPNAGLGGRRPVEMSATSAEYQTVLNLIGRLEHGVSV

Download         Length: 450 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References