Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | slvAT/RES(toxin) |
| Location | 3163760..3164706 | Replicon | chromosome |
| Accession | NZ_CP110535 | ||
| Organism | Halomonas sp. BDJS001 | ||
Toxin (Protein)
| Gene name | slvT | Uniprot ID | - |
| Locus tag | OM794_RS14675 | Protein ID | WP_226247074.1 |
| Coordinates | 3163760..3164278 (-) | Length | 173 a.a. |
Antitoxin (Protein)
| Gene name | slvA | Uniprot ID | - |
| Locus tag | OM794_RS14680 | Protein ID | WP_226247075.1 |
| Coordinates | 3164275..3164706 (-) | Length | 144 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OM794_RS14645 (OM794_14645) | 3159016..3159288 | + | 273 | WP_008958942.1 | XRE family transcriptional regulator | - |
| OM794_RS14650 (OM794_14650) | 3159343..3159519 | - | 177 | WP_226247069.1 | hypothetical protein | - |
| OM794_RS14655 (OM794_14655) | 3159919..3161115 | - | 1197 | WP_226247071.1 | chromate efflux transporter | - |
| OM794_RS14660 (OM794_14660) | 3161228..3162910 | - | 1683 | WP_226247072.1 | dihydroxy-acid dehydratase | - |
| OM794_RS14665 (OM794_14665) | 3163082..3163347 | + | 266 | Protein_2871 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| OM794_RS14670 (OM794_14670) | 3163352..3163666 | + | 315 | WP_226247073.1 | putative addiction module antidote protein | - |
| OM794_RS14675 (OM794_14675) | 3163760..3164278 | - | 519 | WP_226247074.1 | RES domain-containing protein | Toxin |
| OM794_RS14680 (OM794_14680) | 3164275..3164706 | - | 432 | WP_226247075.1 | MbcA/ParS/Xre antitoxin family protein | Antitoxin |
| OM794_RS14685 (OM794_14685) | 3164885..3168517 | + | 3633 | WP_226247076.1 | exodeoxyribonuclease V subunit gamma | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 173 a.a. Molecular weight: 19519.13 Da Isoelectric Point: 5.6204
>T263955 WP_226247074.1 NZ_CP110535:c3164278-3163760 [Halomonas sp. BDJS001]
MIVLPELKTQAYRVHVPRWAFSPTSGAGAREHGGRLNRVGVDALYLSLEEQTALAEYKQLSALMPPGLIVSYTVSVTTII
DFRSGYNSKWDSLWQELNCDWRKYWFNQRIEPPSWLLGDMALEQGVKGILFPSLAHASGTNLVLYTETLTEYDSLEVYDP
KGDLPHNARSWQ
MIVLPELKTQAYRVHVPRWAFSPTSGAGAREHGGRLNRVGVDALYLSLEEQTALAEYKQLSALMPPGLIVSYTVSVTTII
DFRSGYNSKWDSLWQELNCDWRKYWFNQRIEPPSWLLGDMALEQGVKGILFPSLAHASGTNLVLYTETLTEYDSLEVYDP
KGDLPHNARSWQ
Download Length: 519 bp
Antitoxin
Download Length: 144 a.a. Molecular weight: 15856.84 Da Isoelectric Point: 5.6199
>AT263955 WP_226247075.1 NZ_CP110535:c3164706-3164275 [Halomonas sp. BDJS001]
MAIDTVKESLNESSGYLVPDSFERFLADLKGAAREDRHPLINPKLFASALSIDIQTLASQAHVHRTTISRAQGAEKLQRY
LRDALRVLGAAADINGDFHDALFWFRNEPLSAFDYKTPEQLVSEGRAEDLLRYVQALQAGVAG
MAIDTVKESLNESSGYLVPDSFERFLADLKGAAREDRHPLINPKLFASALSIDIQTLASQAHVHRTTISRAQGAEKLQRY
LRDALRVLGAAADINGDFHDALFWFRNEPLSAFDYKTPEQLVSEGRAEDLLRYVQALQAGVAG
Download Length: 432 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|