Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 926356..927473 Replicon chromosome
Accession NZ_CP110535
Organism Halomonas sp. BDJS001

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag OM794_RS04425 Protein ID WP_226247991.1
Coordinates 926730..927473 (+) Length 248 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag OM794_RS04420 Protein ID WP_226247989.1
Coordinates 926356..926727 (+) Length 124 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OM794_RS04400 (OM794_04400) 921521..922495 + 975 WP_226247981.1 DUF2157 domain-containing protein -
OM794_RS04405 (OM794_04405) 922492..923574 + 1083 WP_226247983.1 DUF4401 domain-containing protein -
OM794_RS04410 (OM794_04410) 923571..924110 + 540 WP_226247985.1 GDYXXLXY domain-containing protein -
OM794_RS04415 (OM794_04415) 924270..925997 + 1728 WP_226247987.1 mechanosensitive ion channel -
OM794_RS04420 (OM794_04420) 926356..926727 + 372 WP_226247989.1 DUF2384 domain-containing protein Antitoxin
OM794_RS04425 (OM794_04425) 926730..927473 + 744 WP_226247991.1 RES family NAD+ phosphorylase Toxin
OM794_RS04430 (OM794_04430) 927559..928314 + 756 WP_226247993.1 acyl-CoA thioester hydrolase/BAAT C-terminal domain-containing protein -
OM794_RS04435 (OM794_04435) 928388..928882 + 495 WP_264167791.1 LysE family translocator -
OM794_RS04440 (OM794_04440) 929136..929630 - 495 WP_226247995.1 RidA family protein -
OM794_RS04445 (OM794_04445) 929693..930094 - 402 WP_226247997.1 cytochrome c -
OM794_RS04450 (OM794_04450) 930107..931693 - 1587 WP_226247999.1 flavin monoamine oxidase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(60-204)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(9-68)


Sequences

Toxin        


Download         Length: 248 a.a.        Molecular weight: 27971.72 Da        Isoelectric Point: 4.6816

>T263954 WP_226247991.1 NZ_CP110535:926730-927473 [Halomonas sp. BDJS001]
VWEACGGARNIEPISGTLYRLVESQEQVATLSYVDTLEEQEMLEALLETAKPPYPEQERDLHYLLKTPFRYPPLKWGSRF
GRTFEPSIFYGGKSIVTTLAESAFYRLVFWGSMEGEPVAESLRSEHTLFSVDYAVKWGVRLNAGPFIEHLDVLKQPVDYT
PCQQLGSAMRTANVEAFEYASARDVQGGACVGLFTPEVFKQHEPTDMRPWLCVTNADQVSFKRKDALGVYTYYLNDFLYN
GVLPLPA

Download         Length: 744 bp

Antitoxin


Download         Length: 124 a.a.        Molecular weight: 13412.77 Da        Isoelectric Point: 11.0983

>AT263954 WP_226247989.1 NZ_CP110535:926356-926727 [Halomonas sp. BDJS001]
MPALSQTKPTPEMVLAKAVLRAAEQLGLSQSDLAEVLGVHRTTITQLKKSLKLDPNSKQGELALLLIRLARALFALTGGD
HAWIQHFMRTSNRVTGGIPAEQVTRLEGLFAVLRFVDGMRGKV

Download         Length: 372 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References