Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3857533..3858190 Replicon chromosome
Accession NZ_CP110534
Organism Enterobacter roggenkampii strain WS28-4

Toxin (Protein)


Gene name cptA Uniprot ID A0A1H8U0Q4
Locus tag OM420_RS18145 Protein ID WP_021242050.1
Coordinates 3857533..3857943 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID W7NX65
Locus tag OM420_RS18150 Protein ID WP_006178375.1
Coordinates 3857924..3858190 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OM420_RS18125 (OM420_18120) 3853526..3855259 - 1734 WP_094944166.1 single-stranded-DNA-specific exonuclease RecJ -
OM420_RS18130 (OM420_18125) 3855265..3855978 - 714 WP_021242049.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
OM420_RS18135 (OM420_18130) 3856007..3856903 - 897 WP_008499709.1 site-specific tyrosine recombinase XerD -
OM420_RS18140 (OM420_18135) 3857005..3857526 + 522 WP_008499710.1 flavodoxin FldB -
OM420_RS18145 (OM420_18140) 3857533..3857943 - 411 WP_021242050.1 protein YgfX Toxin
OM420_RS18150 (OM420_18145) 3857924..3858190 - 267 WP_006178375.1 FAD assembly factor SdhE Antitoxin
OM420_RS18155 (OM420_18150) 3858485..3859465 + 981 WP_047745992.1 tRNA-modifying protein YgfZ -
OM420_RS18160 (OM420_18155) 3859550..3860209 - 660 WP_021242052.1 hemolysin III family protein -
OM420_RS18165 (OM420_18160) 3860475..3861206 + 732 WP_094944346.1 MurR/RpiR family transcriptional regulator -
OM420_RS18170 (OM420_18165) 3861323..3862756 + 1434 WP_023294510.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16097.08 Da        Isoelectric Point: 10.9468

>T263950 WP_021242050.1 NZ_CP110534:c3857943-3857533 [Enterobacter roggenkampii]
VVLWQSDLRVSWRSQWMSLLLHGLVAAFVLLMPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLLMDSRLRWQGK
EWDILGMPWMLNCGMMLRLRKVDGGRCQHLWLAADSMDAAEWRDLRRMLLQQTTQG

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10569.05 Da        Isoelectric Point: 5.1340

>AT263950 WP_006178375.1 NZ_CP110534:c3858190-3857924 [Enterobacter roggenkampii]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDTLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1H8U0Q4

Antitoxin

Source ID Structure
AlphaFold DB W7NX65

References