Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-MazE
Location 2972964..2973554 Replicon chromosome
Accession NZ_CP110534
Organism Enterobacter roggenkampii strain WS28-4

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag OM420_RS14120 Protein ID WP_094943135.1
Coordinates 2972964..2973296 (-) Length 111 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag OM420_RS14125 Protein ID WP_094919038.1
Coordinates 2973297..2973554 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OM420_RS14105 (OM420_14100) 2969128..2970453 + 1326 WP_032675143.1 SidA/IucD/PvdA family monooxygenase -
OM420_RS14110 (OM420_14105) 2970480..2972669 + 2190 WP_008499481.1 TonB-dependent siderophore receptor -
OM420_RS14120 (OM420_14115) 2972964..2973296 - 333 WP_094943135.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
OM420_RS14125 (OM420_14120) 2973297..2973554 - 258 WP_094919038.1 antitoxin Antitoxin
OM420_RS14130 (OM420_14125) 2974226..2978125 + 3900 WP_094943138.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-108)

Antitoxin

Antitoxin PemI-like

(4-84)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 11816.70 Da        Isoelectric Point: 10.2965

>T263949 WP_094943135.1 NZ_CP110534:c2973296-2972964 [Enterobacter roggenkampii]
MERGEIWLVSLDPSAGHEQSGKRPVLIVSKASFNKLTRLPVVVPVTSGGNFARTAGFTVSLEGAGTKTMGVIRCDQPRTI
DMAARNGMRLERIPDAVVNEVLARLDAILS

Download         Length: 333 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9422.88 Da        Isoelectric Point: 4.4607

>AT263949 WP_094919038.1 NZ_CP110534:c2973554-2973297 [Enterobacter roggenkampii]
MYTTRLKKVGGSIMLAVPPAVLKTLELSTDSEVGMTINNGCLIIEPQKRPHYSLEELLAQCDPHAEMSEEDREWIDAPAV
GKELL

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References