Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3862094..3862751 Replicon chromosome
Accession NZ_CP110533
Organism Enterobacter quasiroggenkampii strain WS12-3

Toxin (Protein)


Gene name cptA Uniprot ID A0A1H8U0Q4
Locus tag OM418_RS18185 Protein ID WP_021242050.1
Coordinates 3862094..3862504 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID W7NX65
Locus tag OM418_RS18190 Protein ID WP_006178375.1
Coordinates 3862485..3862751 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OM418_RS18165 (OM418_18170) 3858087..3859820 - 1734 WP_277718051.1 single-stranded-DNA-specific exonuclease RecJ -
OM418_RS18170 (OM418_18175) 3859826..3860539 - 714 WP_023333302.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
OM418_RS18175 (OM418_18180) 3860568..3861464 - 897 WP_008499709.1 site-specific tyrosine recombinase XerD -
OM418_RS18180 (OM418_18185) 3861566..3862087 + 522 WP_277718052.1 flavodoxin FldB -
OM418_RS18185 (OM418_18190) 3862094..3862504 - 411 WP_021242050.1 protein YgfX Toxin
OM418_RS18190 (OM418_18195) 3862485..3862751 - 267 WP_006178375.1 FAD assembly factor SdhE Antitoxin
OM418_RS18195 (OM418_18200) 3863046..3864026 + 981 WP_045909913.1 tRNA-modifying protein YgfZ -
OM418_RS18200 (OM418_18205) 3864111..3864770 - 660 WP_045335239.1 hemolysin III family protein -
OM418_RS18205 (OM418_18210) 3865036..3865767 + 732 WP_208763929.1 MurR/RpiR family transcriptional regulator -
OM418_RS18210 (OM418_18215) 3865884..3867317 + 1434 WP_048224765.1 6-phospho-beta-glucosidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16097.08 Da        Isoelectric Point: 10.9468

>T263938 WP_021242050.1 NZ_CP110533:c3862504-3862094 [Enterobacter quasiroggenkampii]
VVLWQSDLRVSWRSQWMSLLLHGLVAAFVLLMPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLLMDSRLRWQGK
EWDILGMPWMLNCGMMLRLRKVDGGRCQHLWLAADSMDAAEWRDLRRMLLQQTTQG

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10569.05 Da        Isoelectric Point: 5.1340

>AT263938 WP_006178375.1 NZ_CP110533:c3862751-3862485 [Enterobacter quasiroggenkampii]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDTLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1H8U0Q4

Antitoxin

Source ID Structure
AlphaFold DB W7NX65

References