Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 251200..251796 Replicon chromosome
Accession NZ_CP110532
Organism Enterobacter roggenkampii strain ws6-3

Toxin (Protein)


Gene name PumA Uniprot ID A0A855LXZ0
Locus tag OM095_RS01130 Protein ID WP_058653792.1
Coordinates 251494..251796 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag OM095_RS01125 Protein ID WP_095429397.1
Coordinates 251200..251487 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OM095_RS01120 (OM095_01120) 249572..251203 + 1632 WP_008503411.1 Na/Pi cotransporter family protein -
OM095_RS01125 (OM095_01125) 251200..251487 - 288 WP_095429397.1 putative addiction module antidote protein Antitoxin
OM095_RS01130 (OM095_01130) 251494..251796 - 303 WP_058653792.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OM095_RS01135 (OM095_01135) 251994..252866 + 873 WP_008503414.1 23S rRNA pseudouridine(2604) synthase RluF -
OM095_RS01140 (OM095_01140) 252867..253139 - 273 WP_014830263.1 DUF3811 domain-containing protein -
OM095_RS01145 (OM095_01145) 253190..254134 - 945 WP_023293551.1 ketopantoate/pantoate/pantothenate transporter PanS -
OM095_RS01150 (OM095_01150) 254240..255814 - 1575 WP_039024657.1 RNA repair transcriptional activator RtcR -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-93)

Antitoxin

Uncharacterized protein HI1420

(3-90)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11485.27 Da        Isoelectric Point: 10.0625

>T263921 WP_058653792.1 NZ_CP110532:c251796-251494 [Enterobacter roggenkampii]
MKEIVQTESFRRWEQNLKDRRAKTIIASRLFRLANGLAGDVKPVGEGISELRIYFGPGYRIYFKDQGNYIIVLLCGGDKS
SQARDILMAKMLSNVSQWQE

Download         Length: 303 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10142.50 Da        Isoelectric Point: 5.6306

>AT263921 WP_095429397.1 NZ_CP110532:c251487-251200 [Enterobacter roggenkampii]
MHKLTPYDPANALVDDEEIAVFIADALETGDSTYIAKALGVVARAKGMSNISQQTGLSREQLYRSFSDKGNPTLNTTLAV
MKALGFGLTLKHAGD

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A855LXZ0

Antitoxin

Source ID Structure

References