Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1831266..1831411 Replicon chromosome
Accession NZ_CP110523
Organism Klebsiella pneumoniae strain WS_29-2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1831302..1831404 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1831266..1831411 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OM422_RS08915 1826396..1828456 + 2061 WP_004151449.1 oligopeptidase B -
OM422_RS08920 1828460..1829119 - 660 WP_002911407.1 exodeoxyribonuclease X -
OM422_RS08925 1829198..1829428 - 231 WP_002911406.1 DNA polymerase III subunit theta -
OM422_RS08930 1829541..1829915 + 375 WP_004151448.1 CopC domain-containing protein YobA -
OM422_RS08935 1829919..1830788 + 870 WP_023280292.1 copper homeostasis membrane protein CopD -
OM422_RS08940 1830805..1831143 + 339 WP_002911404.1 YebY family protein -
- 1831266..1831411 - 146 - - Antitoxin
- 1831302..1831404 + 103 - - Toxin
OM422_RS08945 1831780..1831923 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
OM422_RS08950 1832028..1832996 - 969 WP_004151446.1 VirK/YbjX family protein -
OM422_RS08955 1833153..1833536 + 384 Protein_1745 metallophosphoesterase -
OM422_RS08960 1833620..1834645 + 1026 WP_001101446.1 IS110 family transposase -
OM422_RS08965 1834940..1835908 + 969 WP_072193960.1 IS5 family transposase -
OM422_RS08970 1835964..1836245 + 282 Protein_1748 serine/threonine-protein phosphatase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1826429..1838274 11845


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T263896 NZ_CP110523:1831302-1831404 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT263896 NZ_CP110523:c1831411-1831266 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References