Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1831121..1831266 | Replicon | chromosome |
| Accession | NZ_CP110514 | ||
| Organism | Klebsiella pneumoniae strain WS_29-1 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1831157..1831259 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1831121..1831266 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OM421_RS08915 | 1826251..1828311 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| OM421_RS08920 | 1828315..1828974 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| OM421_RS08925 | 1829053..1829283 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| OM421_RS08930 | 1829396..1829770 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| OM421_RS08935 | 1829774..1830643 | + | 870 | WP_023280292.1 | copper homeostasis membrane protein CopD | - |
| OM421_RS08940 | 1830660..1830998 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 1831121..1831266 | - | 146 | - | - | Antitoxin |
| - | 1831157..1831259 | + | 103 | - | - | Toxin |
| OM421_RS08945 | 1831635..1831778 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| OM421_RS08950 | 1831883..1832851 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| OM421_RS08955 | 1833008..1833391 | + | 384 | Protein_1746 | metallophosphoesterase | - |
| OM421_RS08960 | 1833475..1834500 | + | 1026 | WP_001101446.1 | IS110 family transposase | - |
| OM421_RS08965 | 1834795..1835763 | + | 969 | WP_072193960.1 | IS5 family transposase | - |
| OM421_RS08970 | 1835819..1836100 | + | 282 | Protein_1749 | serine/threonine-protein phosphatase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 1826284..1838129 | 11845 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T263869 NZ_CP110514:1831157-1831259 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT263869 NZ_CP110514:c1831266-1831121 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT