Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-HipB
Location 1990376..1991937 Replicon chromosome
Accession NZ_CP110473
Organism Pantoea anthophila strain CL1

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag OJ965_RS11780 Protein ID WP_265135821.1
Coordinates 1990624..1991937 (+) Length 438 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag OJ965_RS11775 Protein ID WP_265135819.1
Coordinates 1990376..1990624 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OJ965_RS11755 (OJ965_11755) 1985626..1987848 + 2223 WP_265135811.1 iron ABC transporter permease -
OJ965_RS11760 (OJ965_11760) 1987845..1988915 + 1071 WP_265135813.1 ABC transporter ATP-binding protein -
OJ965_RS11765 (OJ965_11765) 1988931..1989725 + 795 WP_265135815.1 inositol monophosphatase family protein -
OJ965_RS11770 (OJ965_11770) 1989760..1990188 - 429 WP_265135817.1 GNAT family N-acetyltransferase -
OJ965_RS11775 (OJ965_11775) 1990376..1990624 + 249 WP_265135819.1 type II toxin-antitoxin system antitoxin HipB Antitoxin
OJ965_RS11780 (OJ965_11780) 1990624..1991937 + 1314 WP_265135821.1 type II toxin-antitoxin system HipA family toxin Toxin
OJ965_RS11785 (OJ965_11785) 1992040..1992684 + 645 WP_265135823.1 LysE family translocator -
OJ965_RS11790 (OJ965_11790) 1992833..1994878 + 2046 WP_265135825.1 FUSC family protein -
OJ965_RS11795 (OJ965_11795) 1995101..1995436 - 336 WP_140028550.1 gamma-glutamylcyclotransferase family protein -
OJ965_RS11800 (OJ965_11800) 1995509..1996225 - 717 WP_265135828.1 fimbrial assembly chaperone -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(149-401)

Antitoxin

Cro/C1-type helix-turn-helix domain

(9-54)


Sequences

Toxin        


Download         Length: 438 a.a.        Molecular weight: 48912.82 Da        Isoelectric Point: 9.3733

>T263836 WP_265135821.1 NZ_CP110473:1990624-1991937 [Pantoea anthophila]
MQKLMAWMNGERVGVLTRQRNGAHEFEYDAGWLRSPLARPLSLSMPLQVRPITSAAVINFFDNLLPDSPAIRDRIVARYQ
IKSRQPFDLLQEVGRDSVGATMLLPPEMPLPPLQARYEVLDEARLEKVLSAYQSDIPLGMLREEIDFRISVAGAQEKTAL
LLTDEGWSIPAGATPTSHIIKLPIGEIKQPAATLDMRESVENEYLCLALARALGMAVPQATIIRAGAMRALAVERFDRRW
SRDKTRLIRLPQEDICQALGLPSSTKYESDGGPGIETIMQLLMGSSQAIADRYRFMQFQVFQWLIGATDGHAKNFSLFIK
RGGSYRLTPFYDVISAYPVLGGTGLNKRALKLAMGLCATKGKKMAIDKIYPRHFIATAKRVSFDPASMEEIFDFFIHAFP
QAVVSVRDALPADFPQHIADAIFSHSLIMLERLRHRT

Download         Length: 1314 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9223.51 Da        Isoelectric Point: 5.7833

>AT263836 WP_265135819.1 NZ_CP110473:1990376-1990624 [Pantoea anthophila]
MIYSPIQLANRLKLIRQRNGWTQSELAKKVGLKQATISHFENAPDSTSLATLFKLLQSLELSLEVQEKAAPAPAPFNDED
DW

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References