263833

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 56603..57639 Replicon plasmid unnamed3
Accession NZ_CP110472
Organism Pantoea anthophila strain CL1

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag OJ965_RS02450 Protein ID WP_265135643.1
Coordinates 56603..57178 (-) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID A0A501RV39
Locus tag OJ965_RS02455 Protein ID WP_064691087.1
Coordinates 57178..57639 (-) Length 154 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OJ965_RS02435 (OJ965_02435) 54828..55154 - 327 WP_265135638.1 hypothetical protein -
OJ965_RS02440 (OJ965_02440) 55393..56061 + 669 WP_140034363.1 recombinase family protein -
OJ965_RS02445 (OJ965_02445) 56039..56443 + 405 WP_140034362.1 hypothetical protein -
OJ965_RS02450 (OJ965_02450) 56603..57178 - 576 WP_265135643.1 PIN domain-containing protein Toxin
OJ965_RS02455 (OJ965_02455) 57178..57639 - 462 WP_064691087.1 helix-turn-helix domain-containing protein Antitoxin
OJ965_RS02460 (OJ965_02460) 58080..59588 - 1509 WP_265135647.1 conjugal transfer protein TraG N-terminal domain-containing protein -
OJ965_RS02465 (OJ965_02465) 59588..59971 - 384 WP_265135649.1 hypothetical protein -
OJ965_RS02470 (OJ965_02470) 59968..61422 - 1455 WP_265135651.1 integrating conjugative element protein -
OJ965_RS02475 (OJ965_02475) 61432..62406 - 975 WP_265135653.1 TIGR03756 family integrating conjugative element protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..73397 73397


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-115)

Antitoxin

Helix-turn-helix domain, group 17

(84-132)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21553.83 Da        Isoelectric Point: 4.4863

>T263833 WP_265135643.1 NZ_CP110472:c57178-56603 [Pantoea anthophila]
MNHTPYPVVLDACVLYPSFLRDLLIRLGLTGLYQPKWSATIEDEWQRNLLANRTDLTPEQIQRTAALMNTVVPDAMITGF
EPLIDSVDLPDVDDRHVVAASVRSNSEIIVTFNLKDFPAPALNAFGIEALHPDDFVMDLFDLNRALVLSAVTTQRSNLRR
PPMSVDEYLEALLRQGMAQTVKELSMYRLLI

Download         Length: 576 bp

Antitoxin


Download         Length: 154 a.a.        Molecular weight: 16949.47 Da        Isoelectric Point: 5.9939

>AT263833 WP_064691087.1 NZ_CP110472:c57639-57178 [Pantoea anthophila]
MTNSILDSLSLPAKGEIEAAVRGQRELAAYLSTKMETQKIAIQDADNITHQIELPTSSLTLLMSILGELALGNAVQVVPV
HAELTTQEAANILNVSRPHMVKLLEDGKLPFHKTGRHRRVLFADLMKYKDQRDSESNKAMQELADLSQELGLY

Download         Length: 462 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A501RV39

References