Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 342093..342582 Replicon plasmid pRho-G13
Accession NZ_CP110470
Organism Rhodococcus opacus strain G13

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag ONE62_RS39895 Protein ID WP_265147792.1
Coordinates 342319..342582 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag ONE62_RS39890 Protein ID WP_265147791.1
Coordinates 342093..342329 (-) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ONE62_RS39860 (ONE62_39850) 337817..338463 - 647 Protein_339 phosphate signaling complex protein PhoU -
ONE62_RS39865 (ONE62_39855) 338543..338752 - 210 WP_265147786.1 DUF6308 family protein -
ONE62_RS39870 (ONE62_39860) 339039..339830 - 792 WP_265147787.1 hypothetical protein -
ONE62_RS39875 (ONE62_39865) 339817..340518 - 702 WP_265147788.1 hypothetical protein -
ONE62_RS39880 (ONE62_39870) 340690..340962 - 273 WP_265147789.1 hypothetical protein -
ONE62_RS39885 (ONE62_39875) 341179..341718 - 540 WP_265147790.1 helix-turn-helix domain-containing protein -
ONE62_RS39890 (ONE62_39880) 342093..342329 - 237 WP_265147791.1 CopG family transcriptional regulator Antitoxin
ONE62_RS39895 (ONE62_39885) 342319..342582 - 264 WP_265147792.1 BrnT family toxin Toxin
ONE62_RS39900 (ONE62_39890) 342650..344035 - 1386 WP_265148529.1 NF041680 family putative transposase -
ONE62_RS39905 (ONE62_39895) 344487..345068 + 582 WP_265147793.1 hypothetical protein -
ONE62_RS39910 (ONE62_39900) 346115..346663 + 549 Protein_349 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..1100117 1100117


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(6-80)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10038.39 Da        Isoelectric Point: 7.2033

>T263830 WP_265147792.1 NZ_CP110470:c342582-342319 [Rhodococcus opacus]
MSGFEFDPNKSEANLAKHGIDFLSAQALWRDPHRLEVPARITDEPRWLVIGVIDGKWWSAVVTYRADRIRIISVRRSRDG
EVALYES

Download         Length: 264 bp

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8966.99 Da        Isoelectric Point: 4.6702

>AT263830 WP_265147791.1 NZ_CP110470:c342329-342093 [Rhodococcus opacus]
MRADEFDERFDAGEDVTFALDTARARRPGEEQRRVNVDFPAWMVAELDREATRLGVTRQSLIKVWIAERLERNGSTAA

Download         Length: 237 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References