Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3528497..3529150 Replicon chromosome
Accession NZ_CP110462
Organism Acinetobacter baumannii strain RBH2

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag OMP06_RS16790 Protein ID WP_000607072.1
Coordinates 3528497..3528886 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag OMP06_RS16795 Protein ID WP_001288210.1
Coordinates 3528893..3529150 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OMP06_RS16775 (OMP06_16775) 3523615..3525810 - 2196 WP_001158905.1 TRAP transporter large permease subunit -
OMP06_RS16780 (OMP06_16780) 3525998..3526564 - 567 WP_000651536.1 rhombosortase -
OMP06_RS16785 (OMP06_16785) 3526642..3527727 - 1086 WP_000049106.1 hypothetical protein -
OMP06_RS16790 (OMP06_16790) 3528497..3528886 - 390 WP_000607072.1 membrane protein Toxin
OMP06_RS16795 (OMP06_16795) 3528893..3529150 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
OMP06_RS16800 (OMP06_16800) 3529338..3530510 + 1173 WP_001190549.1 acyl-CoA dehydrogenase family protein -
OMP06_RS16805 (OMP06_16805) 3530559..3532049 - 1491 WP_000415138.1 NAD(P)/FAD-dependent oxidoreductase -
OMP06_RS16810 (OMP06_16810) 3532231..3532608 - 378 WP_001216380.1 50S ribosomal protein L17 -
OMP06_RS16815 (OMP06_16815) 3532627..3533634 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15663.97 Da        Isoelectric Point: 10.3890

>T263826 WP_000607072.1 NZ_CP110462:c3528886-3528497 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAILFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLVDWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT263826 WP_001288210.1 NZ_CP110462:c3529150-3528893 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References