Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2350227..2350461 Replicon chromosome
Accession NZ_CP110404
Organism Shigella sonnei strain S17BD05200

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2350357..2350460 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2350227..2350461 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OKF41_RS11580 2346782..2347444 - 663 WP_000944256.1 exodeoxyribonuclease X -
OKF41_RS11585 2347468..2348124 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
OKF41_RS11590 2348226..2348456 - 231 WP_000916763.1 DNA polymerase III subunit theta -
OKF41_RS11595 2348595..2348969 + 375 WP_000168735.1 CopC domain-containing protein YobA -
OKF41_RS11600 2348973..2349845 + 873 WP_000879296.1 copper homeostasis membrane protein CopD -
OKF41_RS11605 2349858..2350199 + 342 WP_000976476.1 YebY family protein -
- 2350227..2350461 - 235 - - Antitoxin
- 2350357..2350460 + 104 - - Toxin
OKF41_RS11610 2350592..2351668 - 1077 WP_001189101.1 phage integrase Arm DNA-binding domain-containing protein -
OKF41_RS11615 2351705..2351950 - 246 Protein_2253 IS1 family transposase -
OKF41_RS11625 2353331..2354086 - 756 WP_001282649.1 IS21-like element ISSso4 family helper ATPase IstB -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - ipaH9.8 2344725..2380066 35341


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T263810 NZ_CP110404:2350357-2350460 [Shigella sonnei]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT263810 NZ_CP110404:c2350461-2350227 [Shigella sonnei]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References