Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2334440..2334674 Replicon chromosome
Accession NZ_CP110398
Organism Shigella sonnei strain S17BD06357

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2334570..2334673 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2334440..2334674 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OKF40_RS11460 2330995..2331657 - 663 WP_000944256.1 exodeoxyribonuclease X -
OKF40_RS11465 2331681..2332337 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
OKF40_RS11470 2332439..2332669 - 231 WP_000916763.1 DNA polymerase III subunit theta -
OKF40_RS11475 2332808..2333182 + 375 WP_000168735.1 CopC domain-containing protein YobA -
OKF40_RS11480 2333186..2334058 + 873 WP_000879296.1 copper homeostasis membrane protein CopD -
OKF40_RS11485 2334071..2334412 + 342 WP_000976476.1 YebY family protein -
- 2334440..2334674 - 235 - - Antitoxin
- 2334570..2334673 + 104 - - Toxin
OKF40_RS11490 2334805..2335881 - 1077 WP_001189101.1 phage integrase Arm DNA-binding domain-containing protein -
OKF40_RS11495 2335918..2336163 - 246 Protein_2227 IS1 family transposase -
OKF40_RS11505 2337544..2338299 - 756 WP_001282649.1 IS21-like element ISSso4 family helper ATPase IstB -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - ipaH9.8 2328938..2364279 35341


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T263794 NZ_CP110398:2334570-2334673 [Shigella sonnei]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT263794 NZ_CP110398:c2334674-2334440 [Shigella sonnei]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References