Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 1952497..1953136 Replicon chromosome
Accession NZ_CP110395
Organism Paraburkholderia sp. D15

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LFL96_RS08415 Protein ID WP_281000085.1
Coordinates 1952720..1953136 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LFL96_RS08410 Protein ID WP_281000083.1
Coordinates 1952497..1952733 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LFL96_RS08380 (LFL96_08380) 1947711..1948220 - 510 WP_281000071.1 Spy/CpxP family protein refolding chaperone -
LFL96_RS08385 (LFL96_08385) 1948419..1949303 + 885 WP_281000073.1 LysR family transcriptional regulator -
LFL96_RS08390 (LFL96_08390) 1949463..1949921 + 459 WP_281000075.1 Lrp/AsnC family transcriptional regulator -
LFL96_RS08395 (LFL96_08395) 1950178..1951275 + 1098 WP_281000077.1 saccharopine dehydrogenase NADP-binding domain-containing protein -
LFL96_RS08400 (LFL96_08400) 1951414..1952034 - 621 WP_281000079.1 ATP-binding protein -
LFL96_RS08405 (LFL96_08405) 1952031..1952177 - 147 WP_281000081.1 cytochrome bd-I oxidase subunit CydX -
LFL96_RS08410 (LFL96_08410) 1952497..1952733 + 237 WP_281000083.1 DNA-binding protein Antitoxin
LFL96_RS08415 (LFL96_08415) 1952720..1953136 + 417 WP_281000085.1 type II toxin-antitoxin system VapC family toxin Toxin
LFL96_RS08420 (LFL96_08420) 1953224..1953697 + 474 WP_281000087.1 hypothetical protein -
LFL96_RS08425 (LFL96_08425) 1953820..1954797 + 978 WP_281000089.1 magnesium/cobalt transporter CorA -
LFL96_RS08430 (LFL96_08430) 1955220..1956182 + 963 WP_281000091.1 sugar ABC transporter substrate-binding protein -
LFL96_RS08435 (LFL96_08435) 1956671..1957711 + 1041 WP_281000093.1 LacI family DNA-binding transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-121)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15679.19 Da        Isoelectric Point: 10.2689

>T263784 WP_281000085.1 NZ_CP110395:1952720-1953136 [Paraburkholderia sp. D15]
MYLIDTNVISEIRRWERANAGVRRFFRQAEQEGRKLYLSVVTVGELRRGVEQVRYRGDLMQAAVLERWMNTVLKRFAKSI
LSIDEIAAHVWGKLRVPHSEPAVDKLIAATALSCDLVVVTRNVADFAGPGIRVVNPFD

Download         Length: 417 bp

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 9112.11 Da        Isoelectric Point: 4.1953

>AT263784 WP_281000083.1 NZ_CP110395:1952497-1952733 [Paraburkholderia sp. D15]
MANLWVHSVDDTLFDTLVREAEANGRSVEEEHRFILEEALQTVYNRQFIRALMSMPNVGEDADFERVNDRREAPVVFD

Download         Length: 237 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References