Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PemK-MazE
Location 5583450..5583976 Replicon chromosome
Accession NZ_CP110389
Organism Rhodopseudomonas sp. P2A-2r

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag ONR75_RS26995 Protein ID WP_265079954.1
Coordinates 5583653..5583976 (+) Length 108 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag ONR75_RS26990 Protein ID WP_265079953.1
Coordinates 5583450..5583656 (+) Length 69 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ONR75_RS26970 (ONR75_26970) 5579471..5580477 + 1007 Protein_5343 type I glyceraldehyde-3-phosphate dehydrogenase -
ONR75_RS26975 (ONR75_26975) 5580653..5581855 + 1203 WP_265079950.1 phosphoglycerate kinase -
ONR75_RS26980 (ONR75_26980) 5581938..5582156 + 219 WP_265079951.1 hypothetical protein -
ONR75_RS26985 (ONR75_26985) 5582314..5583381 + 1068 WP_265079952.1 fructose-bisphosphate aldolase class II -
ONR75_RS26990 (ONR75_26990) 5583450..5583656 + 207 WP_265079953.1 antitoxin MazE family protein Antitoxin
ONR75_RS26995 (ONR75_26995) 5583653..5583976 + 324 WP_265079954.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
ONR75_RS27000 (ONR75_27000) 5584009..5585042 + 1034 Protein_5349 fructose-bisphosphate aldolase class I -
ONR75_RS27005 (ONR75_27005) 5585049..5585729 + 681 WP_265079955.1 thiamine phosphate synthase -
ONR75_RS27010 (ONR75_27010) 5585738..5586820 + 1083 WP_265079956.1 tetratricopeptide repeat protein -
ONR75_RS27015 (ONR75_27015) 5586926..5587711 + 786 WP_265079957.1 inositol monophosphatase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-102)

Antitoxin

Antitoxin MazE-like

(6-67)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 11584.50 Da        Isoelectric Point: 10.0103

>T263781 WP_265079954.1 NZ_CP110389:5583653-5583976 [Rhodopseudomonas sp. P2A-2r]
MKRGDLVTAVMQGAYGKARPAVIIQATWVEGLNSVTFLPLTSELSTARIFRILVEPTSENGLQVTSQVMADKCATLPRTK
IGPVFGRLASNDMERVDRAFAIFTGLA

Download         Length: 324 bp

Antitoxin


Download         Length: 69 a.a.        Molecular weight: 7587.70 Da        Isoelectric Point: 7.0132

>AT263781 WP_265079953.1 NZ_CP110389:5583450-5583656 [Rhodopseudomonas sp. P2A-2r]
MSDGAKRVRKHREKMRAAGLKPVTIWVPDVNAPDFKAQVARDIAAINASADEKTILDELSEIEIEGWK

Download         Length: 207 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References