Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1864314..1864459 Replicon chromosome
Accession NZ_CP110369
Organism Klebsiella pneumoniae isolate KP7626

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1864350..1864452 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1864314..1864459 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OM094_RS09090 1859444..1861504 + 2061 WP_004151449.1 oligopeptidase B -
OM094_RS09095 1861508..1862167 - 660 WP_002911407.1 exodeoxyribonuclease X -
OM094_RS09100 1862246..1862476 - 231 WP_002911406.1 DNA polymerase III subunit theta -
OM094_RS09105 1862589..1862963 + 375 WP_004151448.1 CopC domain-containing protein YobA -
OM094_RS09110 1862967..1863836 + 870 WP_023282759.1 copper homeostasis membrane protein CopD -
OM094_RS09115 1863853..1864191 + 339 WP_002911404.1 YebY family protein -
- 1864314..1864459 - 146 - - Antitoxin
- 1864350..1864452 + 103 - - Toxin
OM094_RS09120 1864827..1864970 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
OM094_RS09125 1865075..1866043 - 969 WP_004151446.1 VirK/YbjX family protein -
OM094_RS09130 1866200..1866853 + 654 WP_032418800.1 protein-serine/threonine phosphatase -
OM094_RS09135 1866850..1867041 - 192 WP_002911395.1 YebW family protein -
OM094_RS09140 1867139..1867378 - 240 WP_002911393.1 YebV family protein -
OM094_RS09145 1867494..1868927 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T263734 NZ_CP110369:1864350-1864452 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT263734 NZ_CP110369:c1864459-1864314 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References