263727

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 4363211..4364934 Replicon chromosome
Accession NZ_CP110364
Organism Aeromonas veronii strain C4

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag ONR73_RS20710 Protein ID WP_101320441.1
Coordinates 4363211..4363861 (+) Length 217 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag ONR73_RS20715 Protein ID WP_139409885.1
Coordinates 4363861..4364934 (+) Length 358 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ONR73_RS20695 (ONR73_20695) 4358437..4360896 + 2460 WP_265061655.1 type I restriction-modification system subunit M -
ONR73_RS20700 (ONR73_20700) 4360896..4362203 + 1308 WP_265061656.1 restriction endonuclease subunit S -
ONR73_RS20705 (ONR73_20705) 4362200..4363135 + 936 WP_265061657.1 endonuclease NucS -
ONR73_RS20710 (ONR73_20710) 4363211..4363861 + 651 WP_101320441.1 DUF4433 domain-containing protein Toxin
ONR73_RS20715 (ONR73_20715) 4363861..4364934 + 1074 WP_139409885.1 macro domain-containing protein Antitoxin
ONR73_RS20720 (ONR73_20720) 4365160..4368270 + 3111 WP_265061658.1 HsdR family type I site-specific deoxyribonuclease -
ONR73_RS20725 (ONR73_20725) 4368267..4368995 + 729 WP_201987197.1 SprT family zinc-dependent metalloprotease -
ONR73_RS20730 (ONR73_20730) 4369112..4369915 - 804 WP_265061659.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4351646..4372492 20846


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(17-216)

Antitoxin

Macro domain

(18-131)


Sequences

Toxin        


Download         Length: 217 a.a.        Molecular weight: 24976.38 Da        Isoelectric Point: 6.2208

>T263727 WP_101320441.1 NZ_CP110364:4363211-4363861 [Aeromonas veronii]
MPYDYSGTLNPDKALIFRIVHRDNLPWILANGLWAGNSAEKSDSWVHIGLTELINKRAHHPVPLAPYGVLNDYVPFYFTP
FSPMLSNIHAGRGVPRRDNDEILVLVSSLHRMAELELAFLFTDSHAYYQWANFYDDLGELNRIDWPILQRRDFKRDPDDP
AKFERYQAEALVHQHCPVEALVGVVCYNEETKAKVEQTMVQLGVARPVYVRSGWYF

Download         Length: 651 bp

Antitoxin


Download         Length: 358 a.a.        Molecular weight: 40363.46 Da        Isoelectric Point: 7.2480

>AT263727 WP_139409885.1 NZ_CP110364:4363861-4364934 [Aeromonas veronii]
MIRYTTGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPDNMARYAAACKSGQVTTGKMFITETGELLGPRWIINFPTK
QHWRSPSQMAWIQEGLQDLRHWLVQNHVKSIAIPPLGAGNGGLPWPEVKQAIEEALGDLDIEILLFEPSNQYQNVAKRTG
VEHLTPARALIAELVRRYWFLGMECSLLEIQKLAWFLERFIRQTAPQDPLQLHFTAHHYGPYANNLAHLLNAMDGSYLKS
DKRIPDSKPFDVIWFNDDKKQQLATYLHTEARAYLPALEQAAALIDGFESPYGMELLATVDWLVNQEGCEPTVEALRAGL
IRWPKGGKWAQRKAKLFDDKSLGIALTRLQQSFPAYH

Download         Length: 1074 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References