Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 4093243..4093796 Replicon chromosome
Accession NZ_CP110362
Organism Dickeya dadantii strain XJ12

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag OL445_RS18425 Protein ID WP_284602302.1
Coordinates 4093482..4093796 (+) Length 105 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag OL445_RS18420 Protein ID WP_284602300.1
Coordinates 4093243..4093479 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OL445_RS18400 4088459..4089136 - 678 WP_284602293.1 hypothetical protein -
OL445_RS18405 4089149..4090264 - 1116 WP_284602295.1 hypothetical protein -
OL445_RS18410 4090268..4091326 - 1059 WP_284602297.1 hypothetical protein -
OL445_RS18415 4091978..4092922 + 945 WP_284602298.1 zincin-like metallopeptidase domain-containing protein -
OL445_RS18420 4093243..4093479 + 237 WP_284602300.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
OL445_RS18425 4093482..4093796 + 315 WP_284602302.1 CcdB family protein Toxin
OL445_RS18430 4093793..4094545 - 753 WP_284602303.1 MobC family replication-relaxation protein -
OL445_RS18435 4094554..4096290 - 1737 WP_284603812.1 type IV secretory system conjugative DNA transfer family protein -
OL445_RS18440 4097055..4097357 - 303 WP_284602304.1 TrbM/KikA/MpfK family conjugal transfer protein -
OL445_RS18445 4097396..4098412 - 1017 WP_284602305.1 P-type DNA transfer ATPase VirB11 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - hcp 4075366..4131542 56176


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-103)

Antitoxin

Post-segregation antitoxin CcdA

(9-78)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11542.51 Da        Isoelectric Point: 7.9859

>T263722 WP_284602302.1 NZ_CP110362:4093482-4093796 [Dickeya dadantii]
MQFTVYVNTGKSVVYPLLLDVTSDIIGQLNRRIVIPLLPVEKYPAGRRPDRLVPVVRLTDGKEYAVMTHELASIPVQALG
AVFCDASQYRNQVKAAIDFLIDGI

Download         Length: 315 bp

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 9036.06 Da        Isoelectric Point: 6.2221

>AT263722 WP_284602300.1 NZ_CP110362:4093243-4093479 [Dickeya dadantii]
MTAKQRNTQSVTMTVERALLVRAREAGINLSATLTTALDAELRQHEAKKWQEENREAIEALNRFHDEHGCFSDEYRTF

Download         Length: 237 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References