263721

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DhiAT/dnstrm_HI1420(antitoxin)
Location 3841503..3842257 Replicon chromosome
Accession NZ_CP110362
Organism Dickeya dadantii strain XJ12

Toxin (Protein)


Gene name dhiT Uniprot ID -
Locus tag OL445_RS17310 Protein ID WP_033111742.1
Coordinates 3841503..3841760 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name dhiA Uniprot ID -
Locus tag OL445_RS17315 Protein ID WP_077246089.1
Coordinates 3841769..3842257 (+) Length 163 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OL445_RS17300 3838265..3840415 - 2151 WP_013317224.1 formate dehydrogenase subunit alpha -
OL445_RS17305 3840450..3840992 - 543 WP_013317225.1 4Fe-4S dicluster domain-containing protein -
OL445_RS17310 3841503..3841760 + 258 WP_033111742.1 DUF4160 domain-containing protein Toxin
OL445_RS17315 3841769..3842257 + 489 WP_077246089.1 addiction module antitoxin Antitoxin
OL445_RS17320 3842333..3842827 - 495 WP_284602148.1 hydrogenase maturation peptidase HycI -
OL445_RS17325 3842820..3843215 - 396 WP_224062780.1 formate hydrogenlyase maturation HycH family protein -
OL445_RS17330 3843212..3844003 - 792 WP_161451815.1 NADH-quinone oxidoreductase subunit B family protein -
OL445_RS17335 3844000..3844569 - 570 WP_038910722.1 hydrogenase 4 subunit H -
OL445_RS17340 3844580..3846307 - 1728 WP_284602149.1 hydrogenase large subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Protein of unknown function DUF4160

(9-73)

Antitoxin

Uncharacterized protein HI1420

(81-157)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9972.56 Da        Isoelectric Point: 7.5550

>T263721 WP_033111742.1 NZ_CP110362:3841503-3841760 [Dickeya dadantii]
MPEIDRLAGLIFYLYFYDDGRHHQPHVHVCYGDDELIIAIDTGIEIEGYLPNSKRKMAIRHINAHRQHLLEMWKLAVKGR
HPGKL

Download         Length: 258 bp

Antitoxin


Download         Length: 163 a.a.        Molecular weight: 17861.46 Da        Isoelectric Point: 6.9790

>AT263721 WP_077246089.1 NZ_CP110362:3841769-3842257 [Dickeya dadantii]
MHKIIDVDVTGDFSLRLTYEDGLICDVDLYQYAPGPVFSNASLFIKFGLLPDGALEWLPDIKISASDLRKKGVYVGHTLA
VRERHFADVISRAFYDAVIENRPEILQAALKTAVEKHGNSTVAKEAGAKSRTSLYKSLNKNTNVSLATVVSLAHTVLQLE
EK

Download         Length: 489 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References