Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 3442178..3442803 Replicon chromosome
Accession NZ_CP110362
Organism Dickeya dadantii strain XJ12

Toxin (Protein)


Gene name Hha Uniprot ID E0SD87
Locus tag OL445_RS15555 Protein ID WP_009114000.1
Coordinates 3442178..3442381 (-) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID E0SD88
Locus tag OL445_RS15560 Protein ID WP_013316870.1
Coordinates 3442435..3442803 (-) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OL445_RS15525 3437837..3438175 + 339 WP_002208627.1 P-II family nitrogen regulator -
OL445_RS15530 3438218..3439510 + 1293 WP_013316866.1 ammonium transporter AmtB -
OL445_RS15535 3439606..3440469 - 864 WP_013316867.1 acyl-CoA thioesterase II -
OL445_RS15540 3440704..3441261 + 558 WP_013316868.1 YbaY family lipoprotein -
OL445_RS15545 3441292..3441621 - 330 WP_033111686.1 MGMT family protein -
OL445_RS15555 3442178..3442381 - 204 WP_009114000.1 HHA domain-containing protein Toxin
OL445_RS15560 3442435..3442803 - 369 WP_013316870.1 Hha toxicity modulator TomB Antitoxin
OL445_RS15565 3443311..3443454 - 144 WP_013316871.1 type B 50S ribosomal protein L36 -
OL445_RS15570 3443470..3443721 - 252 WP_013316872.1 type B 50S ribosomal protein L31 -
OL445_RS15575 3443901..3447047 - 3147 WP_013316873.1 efflux RND transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-118)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8133.51 Da        Isoelectric Point: 8.8500

>T263720 WP_009114000.1 NZ_CP110362:c3442381-3442178 [Dickeya dadantii]
MKKIDYLMRLRKCTTIDTLERVIEKNKYELSNDELEMFYSAADHRLAELTMNKLYDKVPTAVWKYVR

Download         Length: 204 bp

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14242.11 Da        Isoelectric Point: 5.1811

>AT263720 WP_013316870.1 NZ_CP110362:c3442803-3442435 [Dickeya dadantii]
MDEYTPQHYDIAQLRFLCENLHDESIATLGDSSRGWVNDPTSAVNLQLNELIEHIAAFVVTYKIKYPHEAALCERVEKYL
DDTYILFSNYGINDTELRKWQKSKSQLFRMFSEKSICTVVKT

Download         Length: 369 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1X3RNQ0

Antitoxin

Source ID Structure
AlphaFold DB E0SD88

References