Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 976748..977285 Replicon chromosome
Accession NC_017192
Organism Arcobacter sp. L

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag ABLL_RS04790 Protein ID WP_083840902.1
Coordinates 976748..977008 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ABLL_RS04795 Protein ID WP_014473653.1
Coordinates 977001..977285 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ABLL_RS04770 (ABLL_0936) 973225..974283 - 1059 WP_014473648.1 DUF1887 family CARF protein -
ABLL_RS04775 (ABLL_0937) 974937..975266 + 330 WP_014473649.1 hypothetical protein -
ABLL_RS04780 (ABLL_0938) 975353..976177 + 825 WP_014473650.1 metallophosphoesterase -
ABLL_RS04785 (ABLL_0939) 976179..976658 + 480 WP_014473651.1 hypothetical protein -
ABLL_RS04790 (ABLL_0940) 976748..977008 + 261 WP_083840902.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ABLL_RS04795 (ABLL_0941) 977001..977285 + 285 WP_014473653.1 putative addiction module antidote protein Antitoxin
ABLL_RS14660 (ABLL_0942) 977374..978327 - 954 WP_014473654.1 nuclease-related domain-containing protein -
ABLL_RS04805 (ABLL_0943) 978415..978792 - 378 WP_014473655.1 hypothetical protein -
ABLL_RS04810 (ABLL_0944) 978882..979325 + 444 WP_014473656.1 hypothetical protein -
ABLL_RS04815 (ABLL_0945) 979341..980156 - 816 WP_014473657.1 hypothetical protein -
ABLL_RS04820 (ABLL_0946) 980168..980518 - 351 WP_014473658.1 SHOCT domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-84)

Antitoxin

Uncharacterized protein HI1420

(4-93)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9661.07 Da        Isoelectric Point: 7.0121

>T26368 WP_083840902.1 NC_017192:976748-977008 [Arcobacter sp. L]
MLKLKDTQGKVAVLRRVEIMKLGNFGDHKSVGNNISELRIPTGPGYRVYYTQKDDEIIVLLVGGDKSSQSDDIKKANEIL
KELENE

Download         Length: 261 bp

>T26368 NC_017192:976748-977008 [Arcobacter sp. L]
TTGTTAAAGCTCAAAGATACTCAAGGTAAAGTTGCAGTATTACGAAGAGTTGAGATAATGAAATTAGGAAACTTTGGAGA
CCATAAATCAGTTGGTAATAATATAAGTGAACTTAGAATTCCAACGGGTCCAGGATATAGAGTTTACTATACTCAAAAAG
ATGATGAAATTATTGTTTTATTAGTTGGTGGTGATAAATCATCACAAAGTGATGATATTAAAAAAGCAAATGAGATTTTA
AAGGAGCTTGAAAATGAGTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10267.81 Da        Isoelectric Point: 4.7672

>AT26368 WP_014473653.1 NC_017192:977001-977285 [Arcobacter sp. L]
MSNVELTNFDIAQYLDNKEVIAEYLSQILADGDMDELLEALGNIAKAKGMSQIASETGLGRESLYKTFHKGTKPKFDTIM
KILGSLGVKVQVTA

Download         Length: 285 bp

>AT26368 NC_017192:977001-977285 [Arcobacter sp. L]
ATGAGTAATGTAGAACTTACAAACTTTGATATAGCACAATATCTTGATAATAAAGAAGTAATAGCAGAATACCTATCTCA
AATCTTAGCAGATGGGGATATGGATGAATTACTAGAAGCTCTTGGAAATATTGCAAAAGCAAAAGGTATGAGCCAAATAG
CAAGTGAAACAGGATTAGGTAGAGAAAGTTTATATAAAACTTTTCATAAAGGTACAAAACCTAAATTTGACACTATTATG
AAAATACTTGGTTCACTTGGTGTTAAAGTTCAAGTTACTGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References