Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | /Xre(antitoxin) |
Location | 4381165..4382422 | Replicon | chromosome |
Accession | NZ_CP110347 | ||
Organism | Pseudomonas aeruginosa strain PALA52 |
Toxin (Protein)
Gene name | - | Uniprot ID | - |
Locus tag | PALA52_RS20185 | Protein ID | WP_058140803.1 |
Coordinates | 4381165..4381920 (-) | Length | 252 a.a. |
Antitoxin (Protein)
Gene name | - | Uniprot ID | V6AJU7 |
Locus tag | PALA52_RS20190 | Protein ID | WP_003086329.1 |
Coordinates | 4382054..4382422 (-) | Length | 123 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PALA52_RS20175 (PALA52_04012) | 4376342..4378885 | + | 2544 | WP_124181096.1 | acyl-homoserine-lactone acylase QuiP | - |
PALA52_RS20180 (PALA52_04013) | 4379032..4380393 | - | 1362 | WP_079752925.1 | DNA recombination protein RmuC | - |
PALA52_RS20185 (PALA52_04014) | 4381165..4381920 | - | 756 | WP_058140803.1 | RES family NAD+ phosphorylase | Toxin |
PALA52_RS20190 (PALA52_04015) | 4382054..4382422 | - | 369 | WP_003086329.1 | DUF2384 domain-containing protein | Antitoxin |
PALA52_RS20195 (PALA52_04016) | 4382495..4383781 | - | 1287 | WP_003112529.1 | FAD-binding oxidoreductase | - |
PALA52_RS20200 (PALA52_04017) | 4383837..4385426 | - | 1590 | WP_263957058.1 | aldehyde dehydrogenase family protein | - |
PALA52_RS20205 (PALA52_04018) | 4385503..4385979 | + | 477 | WP_024915076.1 | elongation factor GreAB | - |
PALA52_RS20210 (PALA52_04019) | 4385982..4386257 | - | 276 | WP_049942684.1 | zinc ribbon domain-containing protein | - |
PALA52_RS20215 (PALA52_04020) | 4386391..4386769 | - | 379 | Protein_4002 | OprD family outer membrane porin | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 252 a.a. Molecular weight: 28341.52 Da Isoelectric Point: 7.7279
>T263655 WP_058140803.1 NZ_CP110347:c4381920-4381165 [Pseudomonas aeruginosa]
VSEIWRQCKGERHIRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMAVPPPSGRILSEHASFEAGWKVERGIRLHVPPFSDHEAALTDIA
DYRAPQELGSAMRSAGVQAFEYRSARCPERGCNVALFTPVAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPYPA
VSEIWRQCKGERHIRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMAVPPPSGRILSEHASFEAGWKVERGIRLHVPPFSDHEAALTDIA
DYRAPQELGSAMRSAGVQAFEYRSARCPERGCNVALFTPVAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPYPA
Download Length: 756 bp
Antitoxin
Download Length: 123 a.a. Molecular weight: 13367.63 Da Isoelectric Point: 9.9874
>AT263655 WP_003086329.1 NZ_CP110347:c4382422-4382054 [Pseudomonas aeruginosa]
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV
Download Length: 369 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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