Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PanAT/DUF4065(antitoxin)
Location 279342..280297 Replicon chromosome
Accession NZ_CP110346
Organism Pseudomonas aeruginosa strain PALA35

Toxin (Protein)


Gene name panT Uniprot ID -
Locus tag PALA35_RS01295 Protein ID WP_170868726.1
Coordinates 279971..280297 (+) Length 109 a.a.

Antitoxin (Protein)


Gene name panA Uniprot ID -
Locus tag PALA35_RS01290 Protein ID WP_023107584.1
Coordinates 279342..279899 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PALA35_RS01265 (PALA35_00253) 274403..274690 - 288 WP_269974655.1 hypothetical protein -
PALA35_RS01270 (PALA35_00254) 274782..275258 - 477 WP_269974656.1 MarR family transcriptional regulator -
PALA35_RS01275 (PALA35_00255) 275299..276789 - 1491 WP_269974657.1 UbiD family decarboxylase HudA -
PALA35_RS01280 (PALA35_00256) 276910..277596 - 687 WP_003106170.1 YoaK family protein -
PALA35_RS01285 (PALA35_00257) 277760..278692 - 933 WP_003084116.1 hypothetical protein -
PALA35_RS01290 (PALA35_00258) 279342..279899 + 558 WP_023107584.1 Panacea domain-containing protein Antitoxin
PALA35_RS01295 (PALA35_00259) 279971..280297 + 327 WP_170868726.1 hypothetical protein Toxin
PALA35_RS01300 (PALA35_00260) 280484..281621 - 1138 Protein_259 IS3 family transposase -
PALA35_RS01305 (PALA35_00262) 281741..283183 - 1443 WP_003133043.1 DUF2875 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin SocA-like, Panacea domain

(28-138)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 12366.33 Da        Isoelectric Point: 8.6957

>T263644 WP_170868726.1 NZ_CP110346:279971-280297 [Pseudomonas aeruginosa]
MNDPVYCPVLGYDAVLLVNISTVYPDKYFDQSCILKKGCHPFVLHDSWVVYREAGPFNLARLEQGVAQKSIKTHQPINAG
DFTRIRAGFDISPDVKIKVERFMRQHKI

Download         Length: 327 bp

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 21377.14 Da        Isoelectric Point: 5.8950

>AT263644 WP_023107584.1 NZ_CP110346:279342-279899 [Pseudomonas aeruginosa]
VIFSEQKVAHMAAFFLASAEGPLPHLTLIKLLYLADRESMARFDVPMSDDRAVSMPHGPVLSSTLDLIKGRLRSEVWSAW
ISPLVDHEVRLVHDVENWDDLDELSRSDRSILESVWQEFGHMTKYQLRDYTHHHIGEWHDPHGSSRDIDPKDTFMALGQS
EELAEIKARDLAERRRHGRKLSEFI

Download         Length: 558 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References