Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 2925250..2926430 Replicon chromosome
Accession NZ_CP110342
Organism Marinobacter sp. AN1

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag LJ360_RS13435 Protein ID WP_264994251.1
Coordinates 2925250..2926068 (-) Length 273 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag LJ360_RS13440 Protein ID WP_218144752.1
Coordinates 2926065..2926430 (-) Length 122 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LJ360_RS13420 (LJ360_13420) 2920710..2922689 - 1980 WP_264994249.1 pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha -
LJ360_RS13425 (LJ360_13425) 2922710..2924440 - 1731 WP_264994250.1 acetate--CoA ligase -
LJ360_RS13430 (LJ360_13430) 2924574..2925047 - 474 WP_091848652.1 thioesterase family protein -
LJ360_RS13435 (LJ360_13435) 2925250..2926068 - 819 WP_264994251.1 RES family NAD+ phosphorylase Toxin
LJ360_RS13440 (LJ360_13440) 2926065..2926430 - 366 WP_218144752.1 MbcA/ParS/Xre antitoxin family protein Antitoxin
LJ360_RS13445 (LJ360_13445) 2926592..2927029 - 438 WP_264994252.1 META domain-containing protein -
LJ360_RS13455 (LJ360_13455) 2927599..2927805 - 207 WP_264994253.1 helix-turn-helix transcriptional regulator -
LJ360_RS13460 (LJ360_13460) 2927957..2928199 + 243 WP_264994254.1 hypothetical protein -
LJ360_RS13465 (LJ360_13465) 2928192..2929427 + 1236 WP_264994255.1 site-specific integrase -
LJ360_RS13470 (LJ360_13470) 2929414..2930364 + 951 WP_264994256.1 TraI domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(59-224)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(71-119)


Sequences

Toxin        


Download         Length: 273 a.a.        Molecular weight: 30551.50 Da        Isoelectric Point: 9.8238

>T263622 WP_264994251.1 NZ_CP110342:c2926068-2925250 [Marinobacter sp. AN1]
MSYLERIYTQTGPLKGQVYRVAETQEKSATTDIVDTAEEQSRLEELLEESKPPYTHPDRGLHYLLKTPFRYPPLRYGSRF
GRVFEKSLFYGSADTQTALSETAYYRLVFVRDTTKPFPRPVKSHHTIFEASVGVEKGLQLQSSAWRDVRDKLTHPSDYAF
TQALGGEMREAGVQAFQFISARAVQVGLRAPDAEDRAAGKSKSGLNAVGLNWGVFTPKAFRRRQPSNFRPMIAVTTREHV
SIVVTERDGTSTAAEFPADRFMVAGQLPRPAV

Download         Length: 819 bp

Antitoxin


Download         Length: 122 a.a.        Molecular weight: 13325.35 Da        Isoelectric Point: 9.8438

>AT263622 WP_218144752.1 NZ_CP110342:c2926430-2926065 [Marinobacter sp. AN1]
MTLAAATQNRTNDRTLLAKALFNAADAMGVAKADVSKIVGRDRTGITRDGIDPQSKSGELALMFVRVYRGLYALVGGDRD
NMRHWLTTDNEYFGQAPLQTMKTCEGLVRVVMYLDAIRGKV

Download         Length: 366 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References