Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/RelE-HTH_26
Location 3916664..3917301 Replicon chromosome
Accession NZ_CP110339
Organism Brucella sp. JSBI001

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LJ361_RS18625 Protein ID WP_151657858.1
Coordinates 3916664..3916918 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LJ361_RS18630 Protein ID WP_151657857.1
Coordinates 3916930..3917301 (+) Length 124 a.a.

Genomic Context


LJ361_RS18595LJ361_RS18600LJ361_RS18605LJ361_RS18610LJ361_RS18615LJ361_RS18620LJ361_RS18625LJ361_RS18630LJ361_RS18635LJ361_RS18640LJ361_RS18645LJ361_RS18650LJ361_RS18655LJ361_RS18660LJ361_RS18665LJ361_RS18670LJ361_RS18675LJ361_RS18680
Location: 3912018..3912308 (291 bp)
Type: Others
Protein ID: WP_063882078.1
Location: 3912301..3912861 (561 bp)
Type: Others
Protein ID: WP_063882077.1
Location: 3912863..3913159 (297 bp)
Type: Others
Protein ID: WP_151657862.1
Location: 3913175..3915391 (2217 bp)
Type: Others
Protein ID: WP_151657861.1
Location: 3915388..3915804 (417 bp)
Type: Others
Protein ID: WP_151657860.1
Location: 3916080..3916643 (564 bp)
Type: Others
Protein ID: WP_151657859.1
Location: 3916664..3916918 (255 bp)
Type: Toxin
Protein ID: WP_151657858.1
Location: 3916930..3917301 (372 bp)
Type: Antitoxin
Protein ID: WP_151657857.1
Location: 3917314..3917892 (579 bp)
Type: Others
Protein ID: WP_151657856.1
Location: 3917933..3918613 (681 bp)
Type: Others
Protein ID: WP_151657855.1
Location: 3918657..3918872 (216 bp)
Type: Others
Protein ID: WP_151657854.1
Location: 3918990..3919355 (366 bp)
Type: Others
Protein ID: WP_151657853.1
Location: 3919760..3919951 (192 bp)
Type: Others
Protein ID: WP_151657851.1
Location: 3920090..3920332 (243 bp)
Type: Others
Protein ID: WP_151657850.1
Location: 3920325..3920780 (456 bp)
Type: Others
Protein ID: WP_151657849.1
Location: 3920791..3921468 (678 bp)
Type: Others
Protein ID: WP_264812082.1
Location: 3921468..3921821 (354 bp)
Type: Others
Protein ID: WP_151657847.1
Location: 3921818..3922204 (387 bp)
Type: Others
Protein ID: WP_151657846.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
LJ361_RS18595 (LJ361_18595)3912018..3912308+291WP_063882078.1hypothetical protein-
LJ361_RS18600 (LJ361_18600)3912301..3912861+561WP_063882077.1hypothetical protein-
LJ361_RS18605 (LJ361_18605)3912863..3913159+297WP_151657862.1hypothetical protein-
LJ361_RS18610 (LJ361_18610)3913175..3915391+2217WP_151657861.1AAA family ATPase-
LJ361_RS18615 (LJ361_18615)3915388..3915804+417WP_151657860.1hypothetical protein-
LJ361_RS18620 (LJ361_18620)3916080..3916643+564WP_151657859.1hypothetical protein-
LJ361_RS18625 (LJ361_18625)3916664..3916918+255WP_151657858.1type II toxin-antitoxin system RelE/ParE family toxinToxin
LJ361_RS18630 (LJ361_18630)3916930..3917301+372WP_151657857.1helix-turn-helix transcriptional regulatorAntitoxin
LJ361_RS18635 (LJ361_18635)3917314..3917892+579WP_151657856.1hypothetical protein-
LJ361_RS18640 (LJ361_18640)3917933..3918613+681WP_151657855.1SOS response-associated peptidase-
LJ361_RS18645 (LJ361_18645)3918657..3918872+216WP_151657854.1hypothetical protein-
LJ361_RS18650 (LJ361_18650)3918990..3919355-366WP_151657853.1thermonuclease family protein-
LJ361_RS18655 (LJ361_18655)3919760..3919951-192WP_151657851.1hypothetical protein-
LJ361_RS18660 (LJ361_18660)3920090..3920332-243WP_151657850.1HTH domain-containing protein-
LJ361_RS18665 (LJ361_18665)3920325..3920780-456WP_151657849.1hypothetical protein-
LJ361_RS18670 (LJ361_18670)3920791..3921468-678WP_264812082.1hypothetical protein-
LJ361_RS18675 (LJ361_18675)3921468..3921821-354WP_151657847.1hypothetical protein-
LJ361_RS18680 (LJ361_18680)3921818..3922204-387WP_151657846.1hypothetical protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideProphage--3899608..395082251214


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 85 a.a.        Molecular weight: 9344.85 Da        Isoelectric Point: 10.2211

>T263619 WP_151657858.1 NZ_CP110339:3916664-3916918 [Brucella sp. JSBI001]
MEQITYSREATKTLIKMPANTAKLIRSKIEQYAADPASLANNVKALKGGEGLLRLRVGDWRVIFTEDGRIIEVIRIAPRG
GAYE

Download         Length: 255 bp


Antitoxin


Download         Length: 124 a.a.        Molecular weight: 13532.54 Da        Isoelectric Point: 4.4987

>AT263619 WP_151657857.1 NZ_CP110339:3916930-3917301 [Brucella sp. JSBI001]
MNVQIIKTPQGEEMAVLPKADYDKLLEAFEDREDIAAARTFREKLAAGEEELIPAEFVNRMIDGENKIKVWRDYRGMSAK
ALAEAAGISAAYLSQIEKGAREGSLDAMKKIAGALCVTIDELV

Download         Length: 372 bp


Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References