263614

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 1146847..1147992 Replicon chromosome
Accession NZ_CP110338
Organism Shewanella algae strain B2215466

Toxin (Protein)


Gene name - Uniprot ID A0A5N5TWA9
Locus tag OLL83_RS05145 Protein ID WP_025011539.1
Coordinates 1147246..1147992 (+) Length 249 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A7X5Z3H2
Locus tag OLL83_RS05140 Protein ID WP_025011540.1
Coordinates 1146847..1147209 (+) Length 121 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OLL83_RS05125 (OLL83_001025) 1144311..1145048 - 738 WP_025011543.1 DsbA family protein -
OLL83_RS05130 (OLL83_001026) 1145189..1145830 - 642 WP_025011542.1 DNA-J related domain-containing protein -
OLL83_RS05135 (OLL83_001027) 1145961..1146614 - 654 WP_025011541.1 oxygen-insensitive NAD(P)H-dependent nitroreductase NfsB -
OLL83_RS05140 (OLL83_001028) 1146847..1147209 + 363 WP_025011540.1 MbcA/ParS/Xre antitoxin family protein Antitoxin
OLL83_RS05145 (OLL83_001029) 1147246..1147992 + 747 WP_025011539.1 RES family NAD+ phosphorylase Toxin
OLL83_RS05150 (OLL83_001030) 1148006..1149571 - 1566 WP_062794000.1 hypothetical protein -
OLL83_RS05155 (OLL83_001031) 1149670..1150395 - 726 WP_025011538.1 amino acid ABC transporter ATP-binding protein -
OLL83_RS05160 (OLL83_001032) 1150388..1151065 - 678 WP_025011537.1 amino acid ABC transporter permease -
OLL83_RS05165 (OLL83_001033) 1151072..1151797 - 726 WP_044735676.1 basic amino acid ABC transporter substrate-binding protein -
OLL83_RS05170 (OLL83_001034) 1152209..1152775 + 567 WP_025011535.1 phosphoribosyltransferase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(55-205)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(69-118)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 28898.66 Da        Isoelectric Point: 4.6921

>T263614 WP_025011539.1 NZ_CP110338:1147246-1147992 [Shewanella algae]
MDFSALEPQDFFPRPYLGRGYRLVESQEEAATLSLVDDFDEQMLLESLLDEVKPPYRSGTEHLHYLLKTPFRYPPLRHGS
RFGSITMESFFYASESWQTCLAEVAYYRFVFMADMLEPYLEPLRSEHMLYSVDINARDCADLTLLQGREVQQQLTHKSNY
TYTQAMGAWLLQQQAQMIRYTSARAEEGVNLALHDPLVLQSTEPQECEYWICQSSADKVAFSRRNSRSMPLTWFLKDFLQ
DGQLPRPA

Download         Length: 747 bp

Antitoxin


Download         Length: 121 a.a.        Molecular weight: 13125.14 Da        Isoelectric Point: 10.4675

>AT263614 WP_025011540.1 NZ_CP110338:1146847-1147209 [Shewanella algae]
MNTLEKANAAEVLFKAFSNACSELQLTQAEASRIIGVNPSTLSRNSGKGFKPDSKQGELQLQLIRLYRSLYAIAGGEKAF
MRHWLNSPNKALNGTPKTLLQTVVGLVSVNQYLDAMRGKV

Download         Length: 363 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7X5Z3H2

References