263611

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 4003129..4003490 Replicon chromosome
Accession NZ_CP110315
Organism Xanthomonas phaseoli pv. phaseoli strain UnB187

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag OM951_RS17735 Protein ID WP_005914328.1
Coordinates 4003129..4003263 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A3Q9Q401
Locus tag OM951_RS17740 Protein ID WP_039568455.1
Coordinates 4003338..4003490 (-) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OM951_RS17715 (OM951_17715) 3999822..4000077 + 256 Protein_3467 hypothetical protein -
OM951_RS17720 (OM951_17720) 4000145..4001089 - 945 WP_039568459.1 MBL fold metallo-hydrolase -
OM951_RS17725 (OM951_17725) 4001219..4002508 - 1290 WP_039568540.1 tryptophan--tRNA ligase -
OM951_RS17730 (OM951_17730) 4002690..4002899 - 210 WP_003486601.1 CsbD family protein -
OM951_RS17735 (OM951_17735) 4003129..4003263 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
OM951_RS17740 (OM951_17740) 4003338..4003490 - 153 WP_039568455.1 entericidin A/B family lipoprotein Antitoxin
OM951_RS17745 (OM951_17745) 4003597..4004520 - 924 WP_041019108.1 arginase -
OM951_RS17750 (OM951_17750) 4004841..4005293 + 453 WP_017158238.1 roadblock/LC7 domain-containing protein -
OM951_RS17755 (OM951_17755) 4005357..4005716 + 360 WP_003486613.1 hypothetical protein -
OM951_RS17760 (OM951_17760) 4005802..4006719 + 918 WP_039568451.1 hypothetical protein -
OM951_RS17765 (OM951_17765) 4006716..4007258 + 543 WP_039568446.1 GTPase -
OM951_RS17770 (OM951_17770) 4007727..4008410 + 684 WP_039568445.1 dTMP kinase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T263611 WP_005914328.1 NZ_CP110315:c4003263-4003129 [Xanthomonas phaseoli pv. phaseoli]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp


Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5138.07 Da        Isoelectric Point: 8.7942

>AT263611 WP_039568455.1 NZ_CP110315:c4003490-4003338 [Xanthomonas phaseoli pv. phaseoli]
MKRLLTLMVLGLFSSGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6


Antitoxin

Source ID Structure
AlphaFold DB A0A3Q9Q401

References