263608

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 4574696..4575057 Replicon chromosome
Accession NZ_CP110313
Organism Xanthomonas phaseoli pv. phaseoli strain BB007a

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag OM954_RS20110 Protein ID WP_005914328.1
Coordinates 4574696..4574830 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A3Q9Q401
Locus tag OM954_RS20115 Protein ID WP_039568455.1
Coordinates 4574905..4575057 (-) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OM954_RS20090 (OM954_20090) 4571389..4571644 + 256 Protein_3938 hypothetical protein -
OM954_RS20095 (OM954_20095) 4571712..4572656 - 945 WP_039568459.1 MBL fold metallo-hydrolase -
OM954_RS20100 (OM954_20100) 4572786..4574075 - 1290 WP_039568540.1 tryptophan--tRNA ligase -
OM954_RS20105 (OM954_20105) 4574257..4574466 - 210 WP_003486601.1 CsbD family protein -
OM954_RS20110 (OM954_20110) 4574696..4574830 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
OM954_RS20115 (OM954_20115) 4574905..4575057 - 153 WP_039568455.1 entericidin A/B family lipoprotein Antitoxin
OM954_RS20120 (OM954_20120) 4575164..4576087 - 924 WP_039568453.1 arginase -
OM954_RS20125 (OM954_20125) 4576408..4576860 + 453 WP_017158238.1 roadblock/LC7 domain-containing protein -
OM954_RS20130 (OM954_20130) 4576924..4577283 + 360 WP_003486613.1 hypothetical protein -
OM954_RS20135 (OM954_20135) 4577380..4578297 + 918 WP_039568451.1 hypothetical protein -
OM954_RS20140 (OM954_20140) 4578294..4578836 + 543 WP_039568446.1 GTPase -
OM954_RS20145 (OM954_20145) 4579305..4579988 + 684 WP_039568445.1 dTMP kinase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T263608 WP_005914328.1 NZ_CP110313:c4574830-4574696 [Xanthomonas phaseoli pv. phaseoli]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp


Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5138.07 Da        Isoelectric Point: 8.7942

>AT263608 WP_039568455.1 NZ_CP110313:c4575057-4574905 [Xanthomonas phaseoli pv. phaseoli]
MKRLLTLMVLGLFSSGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6


Antitoxin

Source ID Structure
AlphaFold DB A0A3Q9Q401

References