Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 38897..39564 Replicon plasmid pC
Accession NZ_CP110311
Organism Xanthomonas phaseoli pv. phaseoli strain CFBP 7423

Toxin (Protein)


Gene name vapC Uniprot ID A0A3T0G501
Locus tag OM947_RS22340 Protein ID WP_022557732.1
Coordinates 38897..39313 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID U4M4Z6
Locus tag OM947_RS22345 Protein ID WP_022557731.1
Coordinates 39310..39564 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OM947_RS22325 (OM947_22325) 36335..36955 - 621 Protein_38 IS3-like element ISXac2 family transposase -
OM947_RS22335 (OM947_22335) 38329..38883 - 555 WP_033482006.1 plasmid pRiA4b ORF-3 family protein -
OM947_RS22340 (OM947_22340) 38897..39313 - 417 WP_022557732.1 type II toxin-antitoxin system VapC family toxin Toxin
OM947_RS22345 (OM947_22345) 39310..39564 - 255 WP_022557731.1 plasmid stability protein Antitoxin
OM947_RS22350 (OM947_22350) 39776..40369 + 594 WP_022560487.1 recombinase family protein -
OM947_RS22355 (OM947_22355) 40366..43395 + 3030 WP_022560486.1 Tn3 family transposase -
OM947_RS22360 (OM947_22360) 43427..43803 - 377 Protein_45 transposase -
OM947_RS22365 (OM947_22365) 44054..44374 + 321 WP_033481941.1 ParC family partition-associated protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..50429 50429
- inside IScluster/Tn - - 29772..49271 19499


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-128)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 14833.04 Da        Isoelectric Point: 4.6812

>T263606 WP_022557732.1 NZ_CP110311:c39313-38897 [Xanthomonas phaseoli pv. phaseoli]
MIVLDTNVVSEAMKPEPHPSVRTWLNDQAAETLYLSSVTLAELLFGIAALPAGKRKDMLEQALDGLMGLFRDRVLPFDID
AARRYAELAVTAKIGGRGFPTPDGYIAAIAASRGFIVASRDTAPYEAAGVTVINPWEG

Download         Length: 417 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9388.80 Da        Isoelectric Point: 8.9326

>AT263606 WP_022557731.1 NZ_CP110311:c39564-39310 [Xanthomonas phaseoli pv. phaseoli]
MAMLTVRNLPDDVHRALRMRAAQNGHSTEAEVREILATAVKPETRVRLGEALAALGRKIGLTNEDFEVFDRVRDKTPAVP
PRLE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3T0G501

Antitoxin

Source ID Structure
AlphaFold DB A0A3T0G545

References