263604

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 4458201..4458562 Replicon chromosome
Accession NZ_CP110309
Organism Xanthomonas phaseoli pv. phaseoli strain CFBP 7423

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag OM947_RS19395 Protein ID WP_005914328.1
Coordinates 4458201..4458335 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A3Q9Q401
Locus tag OM947_RS19400 Protein ID WP_039568455.1
Coordinates 4458410..4458562 (-) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OM947_RS19375 (OM947_19375) 4454895..4455150 + 256 Protein_3795 hypothetical protein -
OM947_RS19380 (OM947_19380) 4455218..4456162 - 945 WP_039568459.1 MBL fold metallo-hydrolase -
OM947_RS19385 (OM947_19385) 4456292..4457581 - 1290 WP_039568540.1 tryptophan--tRNA ligase -
OM947_RS19390 (OM947_19390) 4457762..4457971 - 210 WP_003486601.1 CsbD family protein -
OM947_RS19395 (OM947_19395) 4458201..4458335 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
OM947_RS19400 (OM947_19400) 4458410..4458562 - 153 WP_039568455.1 entericidin A/B family lipoprotein Antitoxin
OM947_RS19405 (OM947_19405) 4458669..4459592 - 924 WP_039568453.1 arginase -
OM947_RS19410 (OM947_19410) 4459913..4460365 + 453 WP_017158238.1 roadblock/LC7 domain-containing protein -
OM947_RS19415 (OM947_19415) 4460429..4460788 + 360 WP_003486613.1 hypothetical protein -
OM947_RS19420 (OM947_19420) 4460885..4461802 + 918 WP_039568451.1 hypothetical protein -
OM947_RS19425 (OM947_19425) 4461799..4462341 + 543 WP_039568446.1 GTPase -
OM947_RS19430 (OM947_19430) 4462810..4463493 + 684 WP_039568445.1 dTMP kinase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T263604 WP_005914328.1 NZ_CP110309:c4458335-4458201 [Xanthomonas phaseoli pv. phaseoli]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp


Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5138.07 Da        Isoelectric Point: 8.7942

>AT263604 WP_039568455.1 NZ_CP110309:c4458562-4458410 [Xanthomonas phaseoli pv. phaseoli]
MKRLLTLMVLGLFSSGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6


Antitoxin

Source ID Structure
AlphaFold DB A0A3Q9Q401

References