263601

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 4424839..4425200 Replicon chromosome
Accession NZ_CP110306
Organism Xanthomonas phaseoli pv. phaseoli strain BB075a

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag OM949_RS19255 Protein ID WP_005914328.1
Coordinates 4424839..4424973 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A3Q9Q401
Locus tag OM949_RS19260 Protein ID WP_039568455.1
Coordinates 4425048..4425200 (-) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OM949_RS19235 (OM949_19235) 4421532..4421787 + 256 Protein_3767 hypothetical protein -
OM949_RS19240 (OM949_19240) 4421855..4422799 - 945 WP_039568459.1 MBL fold metallo-hydrolase -
OM949_RS19245 (OM949_19245) 4422929..4424218 - 1290 WP_039568540.1 tryptophan--tRNA ligase -
OM949_RS19250 (OM949_19250) 4424400..4424609 - 210 WP_003486601.1 CsbD family protein -
OM949_RS19255 (OM949_19255) 4424839..4424973 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
OM949_RS19260 (OM949_19260) 4425048..4425200 - 153 WP_039568455.1 entericidin A/B family lipoprotein Antitoxin
OM949_RS19265 (OM949_19265) 4425307..4426230 - 924 WP_039568453.1 arginase -
OM949_RS19270 (OM949_19270) 4426551..4427003 + 453 WP_017158238.1 roadblock/LC7 domain-containing protein -
OM949_RS19275 (OM949_19275) 4427067..4427426 + 360 WP_003486613.1 hypothetical protein -
OM949_RS19280 (OM949_19280) 4427523..4428440 + 918 WP_039568451.1 hypothetical protein -
OM949_RS19285 (OM949_19285) 4428437..4428979 + 543 WP_039568446.1 GTPase -
OM949_RS19290 (OM949_19290) 4429448..4430131 + 684 WP_039568445.1 dTMP kinase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T263601 WP_005914328.1 NZ_CP110306:c4424973-4424839 [Xanthomonas phaseoli pv. phaseoli]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp


Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5138.07 Da        Isoelectric Point: 8.7942

>AT263601 WP_039568455.1 NZ_CP110306:c4425200-4425048 [Xanthomonas phaseoli pv. phaseoli]
MKRLLTLMVLGLFSSGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6


Antitoxin

Source ID Structure
AlphaFold DB A0A3Q9Q401

References