Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 8189..8856 Replicon plasmid pC
Accession NZ_CP110305
Organism Xanthomonas phaseoli pv. phaseoli strain BB013a

Toxin (Protein)


Gene name vapC Uniprot ID A0A3T0G501
Locus tag OM952_RS22570 Protein ID WP_022557732.1
Coordinates 8189..8605 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID U4M4Z6
Locus tag OM952_RS22575 Protein ID WP_022557731.1
Coordinates 8602..8856 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OM952_RS22550 (OM952_22550) 3770..5944 + 2175 WP_264686316.1 XopC/Rsp1239 family type III secretion system effector -
OM952_RS22555 (OM952_22555) 5905..6273 + 369 WP_264686317.1 hypothetical protein -
OM952_RS22560 (OM952_22560) 6826..7527 - 702 Protein_6 IS3-like element ISXac2 family transposase -
OM952_RS22565 (OM952_22565) 7621..8175 - 555 WP_033482006.1 plasmid pRiA4b ORF-3 family protein -
OM952_RS22570 (OM952_22570) 8189..8605 - 417 WP_022557732.1 type II toxin-antitoxin system VapC family toxin Toxin
OM952_RS22575 (OM952_22575) 8602..8856 - 255 WP_022557731.1 plasmid stability protein Antitoxin
OM952_RS22580 (OM952_22580) 9068..9661 + 594 WP_022560487.1 recombinase family protein -
OM952_RS22585 (OM952_22585) 9658..12687 + 3030 WP_022560486.1 Tn3 family transposase -
OM952_RS22590 (OM952_22590) 12719..13095 - 377 Protein_12 transposase -
OM952_RS22595 (OM952_22595) 13347..13667 + 321 WP_033481941.1 ParC family partition-associated protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..43294 43294
- inside IScluster/Tn - - 1..18564 18563


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-128)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 14833.04 Da        Isoelectric Point: 4.6812

>T263600 WP_022557732.1 NZ_CP110305:c8605-8189 [Xanthomonas phaseoli pv. phaseoli]
MIVLDTNVVSEAMKPEPHPSVRTWLNDQAAETLYLSSVTLAELLFGIAALPAGKRKDMLEQALDGLMGLFRDRVLPFDID
AARRYAELAVTAKIGGRGFPTPDGYIAAIAASRGFIVASRDTAPYEAAGVTVINPWEG

Download         Length: 417 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9388.80 Da        Isoelectric Point: 8.9326

>AT263600 WP_022557731.1 NZ_CP110305:c8856-8602 [Xanthomonas phaseoli pv. phaseoli]
MAMLTVRNLPDDVHRALRMRAAQNGHSTEAEVREILATAVKPETRVRLGEALAALGRKIGLTNEDFEVFDRVRDKTPAVP
PRLE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3T0G501

Antitoxin

Source ID Structure
AlphaFold DB A0A3T0G545

References