Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2824..3491 Replicon plasmid pA
Accession NZ_CP110304
Organism Xanthomonas phaseoli pv. phaseoli strain BB013a

Toxin (Protein)


Gene name vapC Uniprot ID A0A3T0G501
Locus tag OM952_RS22200 Protein ID WP_022557732.1
Coordinates 2824..3240 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID U4M4Z6
Locus tag OM952_RS22205 Protein ID WP_022557731.1
Coordinates 3237..3491 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OM952_RS22185 (OM952_22185) 1447..1995 + 549 WP_022557734.1 DNA topoisomerase -
OM952_RS22190 (OM952_22190) 2044..2181 + 138 Protein_2 transposase -
OM952_RS22195 (OM952_22195) 2256..2810 - 555 WP_033482006.1 plasmid pRiA4b ORF-3 family protein -
OM952_RS22200 (OM952_22200) 2824..3240 - 417 WP_022557732.1 type II toxin-antitoxin system VapC family toxin Toxin
OM952_RS22205 (OM952_22205) 3237..3491 - 255 WP_022557731.1 plasmid stability protein Antitoxin
OM952_RS22210 (OM952_22210) 3703..4296 + 594 WP_022560487.1 recombinase family protein -
OM952_RS22215 (OM952_22215) 4293..7322 + 3030 WP_022560486.1 Tn3 family transposase -
OM952_RS22220 (OM952_22220) 7355..7740 + 386 Protein_8 IS3 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - virB1 1..58785 58785
- inside IScluster/Tn - virB1 2044..19464 17420


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-128)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 14833.04 Da        Isoelectric Point: 4.6812

>T263599 WP_022557732.1 NZ_CP110304:c3240-2824 [Xanthomonas phaseoli pv. phaseoli]
MIVLDTNVVSEAMKPEPHPSVRTWLNDQAAETLYLSSVTLAELLFGIAALPAGKRKDMLEQALDGLMGLFRDRVLPFDID
AARRYAELAVTAKIGGRGFPTPDGYIAAIAASRGFIVASRDTAPYEAAGVTVINPWEG

Download         Length: 417 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9388.80 Da        Isoelectric Point: 8.9326

>AT263599 WP_022557731.1 NZ_CP110304:c3491-3237 [Xanthomonas phaseoli pv. phaseoli]
MAMLTVRNLPDDVHRALRMRAAQNGHSTEAEVREILATAVKPETRVRLGEALAALGRKIGLTNEDFEVFDRVRDKTPAVP
PRLE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3T0G501

Antitoxin

Source ID Structure
AlphaFold DB A0A3T0G545

References