263597

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 4487824..4488185 Replicon chromosome
Accession NZ_CP110303
Organism Xanthomonas phaseoli pv. phaseoli strain BB013a

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag OM952_RS19655 Protein ID WP_005914328.1
Coordinates 4487824..4487958 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A3Q9Q401
Locus tag OM952_RS19660 Protein ID WP_039568455.1
Coordinates 4488033..4488185 (-) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OM952_RS19635 (OM952_19635) 4484517..4484772 + 256 Protein_3848 hypothetical protein -
OM952_RS19640 (OM952_19640) 4484840..4485784 - 945 WP_039568459.1 MBL fold metallo-hydrolase -
OM952_RS19645 (OM952_19645) 4485914..4487203 - 1290 WP_039568540.1 tryptophan--tRNA ligase -
OM952_RS19650 (OM952_19650) 4487385..4487594 - 210 WP_003486601.1 CsbD family protein -
OM952_RS19655 (OM952_19655) 4487824..4487958 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
OM952_RS19660 (OM952_19660) 4488033..4488185 - 153 WP_039568455.1 entericidin A/B family lipoprotein Antitoxin
OM952_RS19665 (OM952_19665) 4488292..4489215 - 924 WP_039568453.1 arginase -
OM952_RS19670 (OM952_19670) 4489536..4489988 + 453 WP_017158238.1 roadblock/LC7 domain-containing protein -
OM952_RS19675 (OM952_19675) 4490052..4490411 + 360 WP_003486613.1 hypothetical protein -
OM952_RS19680 (OM952_19680) 4490508..4491425 + 918 WP_039568451.1 hypothetical protein -
OM952_RS19685 (OM952_19685) 4491422..4491964 + 543 WP_039568446.1 GTPase -
OM952_RS19690 (OM952_19690) 4492433..4493116 + 684 WP_039568445.1 dTMP kinase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T263597 WP_005914328.1 NZ_CP110303:c4487958-4487824 [Xanthomonas phaseoli pv. phaseoli]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp


Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5138.07 Da        Isoelectric Point: 8.7942

>AT263597 WP_039568455.1 NZ_CP110303:c4488185-4488033 [Xanthomonas phaseoli pv. phaseoli]
MKRLLTLMVLGLFSSGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6


Antitoxin

Source ID Structure
AlphaFold DB A0A3Q9Q401

References