263544

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 1305929..1306845 Replicon chromosome
Accession NZ_CP110268
Organism Bacillus siamensis strain YB-1631

Toxin (Protein)


Gene name spoIISA Uniprot ID -
Locus tag OM992_RS06985 Protein ID WP_049628327.1
Coordinates 1306099..1306845 (-) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID I2HQ14
Locus tag OM992_RS06980 Protein ID WP_003154807.1
Coordinates 1305929..1306099 (-) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OM992_RS06940 (1301169) 1301169..1302782 + 1614 WP_264820016.1 hypothetical protein -
OM992_RS06945 (1302795) 1302795..1303175 + 381 WP_064778772.1 XkdW family protein -
OM992_RS06950 (1303179) 1303179..1303376 + 198 WP_045925711.1 XkdX family protein -
OM992_RS06955 (1303425) 1303425..1304186 + 762 WP_064778773.1 hypothetical protein -
OM992_RS06960 (1304238) 1304238..1304501 + 264 WP_031378810.1 hemolysin XhlA family protein -
OM992_RS06965 (1304515) 1304515..1304778 + 264 WP_064778774.1 phage holin -
OM992_RS06970 (1304792) 1304792..1305670 + 879 WP_064778775.1 N-acetylmuramoyl-L-alanine amidase -
OM992_RS06975 (1305707) 1305707..1305832 - 126 WP_141228459.1 hypothetical protein -
OM992_RS06980 (1305929) 1305929..1306099 - 171 WP_003154807.1 type II toxin-antitoxin system SpoIISB family antitoxin Antitoxin
OM992_RS06985 (1306099) 1306099..1306845 - 747 WP_049628327.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
OM992_RS06990 (1306952) 1306952..1307950 - 999 WP_044802872.1 inorganic phosphate transporter -
OM992_RS06995 (1307963) 1307963..1308580 - 618 WP_032874614.1 DUF47 domain-containing protein -
OM992_RS07000 (1308864) 1308864..1310180 - 1317 WP_064778778.1 amino acid permease -
OM992_RS07005 (1310502) 1310502..1311452 + 951 WP_095240851.1 ring-cleaving dioxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(4-239)

Antitoxin

Antitoxin SpoIISB

(1-56)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29080.53 Da        Isoelectric Point: 4.6947

>T263544 WP_049628327.1 NZ_CP110268:c1306845-1306099 [Bacillus siamensis]
MLVFFQIMVWTMAAALILYVYASWRYEAKVKEKMFAIRKTWYLLFVLGSMVYWTYDPESLFSAWRQYLIVAVCFALIDAF
IFLSAYIKKLAGNELETDTREILEENNEMLHSYLEKLKTYQYLLKNEPIHVYYGSTEAYAEGISRLLAAYAEKMNVTASL
CDYSAQSDKDRLTEHMPDAADVQSRLNRKDVYYDQKGRLVLIPFTVQDRHYVIKLTSENLLTEFDYLLFTSLTSIYDLML
PIEEEGDG

Download         Length: 747 bp

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6676.74 Da        Isoelectric Point: 10.9273

>AT263544 WP_003154807.1 NZ_CP110268:c1306099-1305929 [Bacillus siamensis]
MEQAFQNGQPEQRAKPFKMFKKRSMTSIASYQVSPHTARIFKENERLIDKYKQKKA

Download         Length: 171 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB I2HQ14

References