Detailed information of TA system TA026349

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 1281014..1281539
• Replicon: chromosome
• Accession: NC_017187
• Organism: Arcobacter butzleri ED-1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: ABED_RS06405
• Protein ID: WP_014468875.1
• Coordinates: 1281255..1281539 (+)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A0G9JP98
• Locus tag: ABED_RS06400
• Protein ID: WP_014468874.1
• Coordinates: 1281014..1281265 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ABED_RS11125	1277054..1277551	-	498	WP_014468868.1	DUF4373 domain-containing protein	-
ABED_RS06375	1277709..1277948	-	240	WP_014468869.1	helix-turn-helix domain-containing protein	-
ABED_RS06380	1278173..1278565	+	393	WP_014468870.1	hypothetical protein	-
ABED_RS06385	1278558..1279229	+	672	WP_014468871.1	hypothetical protein	-
ABED_RS06390	1279239..1279880	+	642	WP_014468872.1	hypothetical protein	-
ABED_RS11225	1280229..1280681	-	453	WP_014468873.1	hypothetical protein	-
ABED_RS06400	1281014..1281265	+	252	WP_014468874.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
ABED_RS06405	1281255..1281539	+	285	WP_014468875.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (11-71)

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 11243.15 Da
• Isoelectric Point: 10.1830

>T26349 WP_014468875.1 NC_017187:1281255-1281539 [Arcobacter butzleri ED-1]
MTYNLEFKPQALKEWNKLGSTIKEQFKKKLEERLENPKVEKDKLSGYENVYKIKLKTAGYRLAYQVKDEEIVVLVLSVGK
REKDKIYKNLKDRF

Nucleotide

• Length: 285 bp

>T26349 NC_017187:1281255-1281539 [Arcobacter butzleri ED-1]
ATGACTTATAATCTTGAATTTAAACCTCAAGCTTTGAAAGAGTGGAATAAATTAGGCTCAACGATAAAAGAACAATTTAA
AAAGAAATTAGAAGAAAGACTAGAAAATCCAAAAGTAGAAAAAGATAAACTAAGTGGATATGAAAATGTTTATAAAATAA
AACTAAAAACTGCTGGATATAGACTTGCTTATCAAGTTAAAGATGAAGAAATTGTTGTTTTGGTATTGAGTGTTGGAAAA
AGGGAAAAAGATAAAATTTATAAGAATCTAAAAGATAGATTCTGA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9240.60 Da
• Isoelectric Point: 4.3696

>AT26349 WP_014468874.1 NC_017187:1281014-1281265 [Arcobacter butzleri ED-1]
MQPILANYSASITELKKSPTQLLNEADNEVIAILNHNIPSAYLVPSKLYEKMMDIIDDYHLSLEVGKALNDGEKPVKVSL
DDL

Nucleotide

• Length: 252 bp

>AT26349 NC_017187:1281014-1281265 [Arcobacter butzleri ED-1]
ATGCAACCAATTTTAGCAAATTATAGTGCAAGTATAACAGAACTTAAAAAATCACCTACACAATTACTAAATGAAGCAGA
TAATGAAGTTATAGCAATATTAAATCATAATATCCCTAGTGCTTATTTAGTTCCAAGTAAACTTTATGAAAAAATGATGG
ATATTATAGATGATTATCATTTGTCATTAGAAGTAGGAAAAGCTTTAAATGATGGTGAAAAACCAGTTAAAGTAAGTTTA
GATGACTTATAA

Structures

Antitoxin

• AlphaFold DB: A0A0G9JP98