Detailed information of TA system TA026348

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): FicTA/Fic(toxin)
• Location: 1269865..1270806
• Replicon: chromosome
• Accession: NC_017187
• Organism: Arcobacter butzleri ED-1

Toxin (Protein)

• Gene name: Fic
• Uniprot ID: -
• Locus tag: ABED_RS06325
• Protein ID: WP_014468859.1
• Coordinates: 1269865..1270551 (-)
• Length: 229 a.a.

Antitoxin (Protein)

• Gene name: Fti
• Uniprot ID: -
• Locus tag: ABED_RS11165
• Protein ID: WP_014468860.1
• Coordinates: 1270552..1270806 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ABED_RS11250	1265126..1266373	-	1248	WP_014468854.1	rubredoxin	-
ABED_RS11195	1266556..1266702	-	147	WP_014468855.1	hypothetical protein	-
ABED_RS06310	1266918..1268693	-	1776	WP_014468856.1	deoxycytidylate deaminase	-
ABED_RS06315	1269271..1269582	+	312	WP_014468857.1	hypothetical protein	-
ABED_RS06320	1269638..1269853	-	216	WP_014468858.1	hypothetical protein	-
ABED_RS06325	1269865..1270551	-	687	WP_014468859.1	Fic family protein	Toxin
ABED_RS11165	1270552..1270806	-	255	WP_014468860.1	hypothetical protein	Antitoxin
ABED_RS06335	1270847..1271245	-	399	WP_014468861.1	hypothetical protein	-
ABED_RS06340	1271266..1271811	-	546	WP_014468862.1	hypothetical protein	-
ABED_RS06345	1271811..1274303	-	2493	WP_014468863.1	hypothetical protein	-
ABED_RS06350	1274313..1275038	-	726	WP_014468864.1	hypothetical protein	-
ABED_RS06355	1275029..1275256	-	228	WP_014468865.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Fido domain (49-153)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 229 a.a.
• Molecular weight: 26617.46 Da
• Isoelectric Point: 6.1327

>T26348 WP_014468859.1 NC_017187:c1270551-1269865 [Arcobacter butzleri ED-1]
MPVTNDFEKMLLSTNLVKAQDLQDLAIKERELTSKRIFQLKITPIKGSFDYQHLKDIHNYIFKDVYTWAGKDRFDIGLNG
VFLKGNQHFVPGSELPKYSNIIFDELKEQNFLKDCKDINSFAKGIATFMMEINALHPFREGNGRTQRIFLNQLAENADYK
MDLNLISEYKMVTACKLASKLKPEFLENLIKENLNQFNENKDNNFKMSIDELTEYIEQNTPKQNLDLN

Nucleotide

• Length: 687 bp

>T26348 NC_017187:c1270551-1269865 [Arcobacter butzleri ED-1]
ATGCCTGTAACAAATGATTTTGAAAAAATGCTTTTATCTACTAATCTTGTAAAAGCTCAAGACTTACAAGATTTAGCAAT
AAAGGAAAGAGAACTAACAAGTAAAAGAATTTTTCAATTAAAAATAACTCCTATAAAAGGAAGTTTTGATTATCAACACT
TAAAAGATATTCATAATTATATTTTTAAAGATGTTTATACTTGGGCTGGAAAAGATAGATTTGATATTGGTTTAAATGGA
GTATTTTTAAAAGGAAATCAACACTTTGTTCCAGGTAGTGAATTACCAAAATATTCAAATATAATTTTTGATGAATTAAA
AGAACAAAACTTTTTAAAAGATTGTAAAGATATTAATTCCTTTGCAAAAGGTATTGCTACTTTCATGATGGAAATAAATG
CTTTACACCCATTTCGTGAAGGTAATGGTAGAACACAAAGAATATTTTTAAATCAGTTAGCAGAAAATGCTGATTATAAA
ATGGATTTAAATCTTATTTCTGAATATAAAATGGTTACAGCTTGTAAATTAGCTTCAAAACTAAAACCTGAATTTCTTGA
AAATCTTATAAAAGAAAATTTAAACCAATTTAATGAAAATAAAGATAATAATTTTAAAATGAGTATAGATGAATTAACTG
AATATATAGAACAAAATACACCAAAACAAAATTTAGATTTAAATTAA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9588.90 Da
• Isoelectric Point: 4.4367

>AT26348 WP_014468860.1 NC_017187:c1270806-1270552 [Arcobacter butzleri ED-1]
MKKTINTTTYPEVYTLAESLAILDKYKDDLTEEQFNNIKSVISSFAIESMYLNEKDILDGIKIQKGEATADELIANQKRN
WGIL

Nucleotide

• Length: 255 bp

>AT26348 NC_017187:c1270806-1270552 [Arcobacter butzleri ED-1]
ATGAAAAAGACTATAAATACAACAACTTATCCTGAAGTTTATACTTTAGCTGAAAGTTTAGCTATTTTAGATAAATATAA
AGATGATTTAACAGAAGAACAGTTTAATAATATAAAATCAGTTATAAGTAGCTTTGCTATTGAAAGTATGTATCTAAATG
AAAAAGATATTTTAGATGGAATTAAAATACAAAAAGGTGAAGCAACAGCCGATGAATTAATAGCTAATCAAAAAAGAAAT
TGGGGTATTTTATAA